10173-01-0

Basic information

• Product Name: 3,3',6-Trimethoxy-4',5,7-trihydroxyflavone
• Synonyms: 2-(3-Methoxy-4-hydroxyphenyl)-3,6-dimethoxy-5,7-dihydroxy-4H-1-benzopyran-4-one;3,3',6-Trimethoxy-4',5,7-trihydroxyflavone;4',5,7-Trihydroxy-3,3',6-trimethoxyflavone;5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one;Jaceidin;Quercetagetin 3,3',6-trimethyl ether
• CAS NO: 10173-01-0
• Molecular Formula: C₁₈H₁₆O₈
• Molecular Weight: 360.3148
• Mol File: 10173-01-0.mol

Chemical Properties

• Boiling Point: 647.8°Cat760mmHg
• Flash Point: 238.3°C
• Appearance: /
• Density: 1.54g/cm³
• Vapor Pressure: 2.22E-17mmHg at 25°C
• Refractive Index: 1.68
• CAS DataBase Reference: 3,3',6-Trimethoxy-4',5,7-trihydroxyflavone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3',6-Trimethoxy-4',5,7-trihydroxyflavone(10173-01-0)
• EPA Substance Registry System: 3,3',6-Trimethoxy-4',5,7-trihydroxyflavone(10173-01-0)

Safety Data

• Hazardous Substances Data: 10173-01-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
3,3',6-Trimethoxy-4',5,7-trihydroxyflavone is utilized as a key component in the research and development of new pharmaceutical drugs. Its anti-inflammatory and antioxidant properties make it a promising candidate for treating various inflammatory and oxidative stress-related conditions.
Used in Cancer Treatment:
In the field of oncology, 3,3',6-Trimethoxy-4',5,7-trihydroxyflavone is employed as a potential anticancer agent. Its ability to inhibit the growth of cancer cells positions it as a valuable asset in the search for novel cancer therapies.
Used in Cosmetic Products:
3,3',6-Trimethoxy-4',5,7-trihydroxyflavone is also explored for its potential use in the cosmetics industry. Its antioxidant properties may contribute to the development of products that promote skin health and protect against environmental stressors.
Used in Antioxidant Applications:
3,3',6-Trimethoxy-4',5,7-trihydroxyflavone is used as an antioxidant agent for its capacity to neutralize free radicals, thereby potentially reducing oxidative stress and associated cellular damage.
Used in Anti-Inflammatory Applications:
This flavonoid is used as an anti-inflammatory agent, leveraging its ability to reduce inflammation, which can be beneficial in managing inflammatory conditions.

InChI:InChI=1/C18H16O8/c1-23-11-6-8(4-5-9(11)19)16-18(25-3)15(22)13-12(26-16)7-10(20)17(24-2)14(13)21/h4-7,19-21H,1-3H3

Relevant articles and documents

FLAVONOIDS FROM THE TWIGS OF EUCRYPHIA GLUTINOSA

The rare dihydroquercetin 3-O-β-D-xyloside, caryatin 7-O-β-D-glucoside and the previously unknown 6-methoxylated flavonoid glycoside jaceidin 5-O-β-D-glucoside were isolated from the twigs of Eucryphia glutinosa where they co-occur with the widespread reynoutrin. Key words: Eucryphia glutinosa; Eucryphiaceae; twigs; flavonoids; dihydroquercetin 3-O-β-D-xyloside; reynoutrin; jaceidin 5-O-β-D-glucoside; caryatin 7-O-β-D-glucoside.

THREE HIGHLY OXYGENATED FLAVONE GLUCURONIDES IN LEAVES OF SPINACIA OLERACEA

Droplet counter-current chromatographic separation and subsequent TLC demonstrated the existence of at least 14 phenolics in the leaves of Spinacia oleracea.Three have now been isolated and identified, respectively, as the 4'-glucuronides of 5,7,4'-trihydroxy-3,6,3'-trimethoxyflavone (jaceidin), 5,3',4'-trihydroxy-3-methoxy-6:7-methylenedioxyflavone and 5,4'-dihydroxy-3,3'-dimethoxy-6:7-methylenedioxyflavone.Key Word Index- Spinacia oleracea; Chenopodiaceae; spinach; jaceidin; 4'-glucuronide; 5,3',4'-trihydroxy-3-methoxy-6:7-methylenedioxyflavone 4'-glucuronide; 5,4'-dihydroxy-3,3'-dimethoxy-6:7-methylenedioxyflavone 4'-glucuronide; 1H NMR; 13C NMR; FABMS.