1018817-74-7

Basic information

• Product Name: 5-(3-chlorophenyl)-1-methyl-3-phenyl-4,5-dihydro-1H-pyrazole
• CAS NO: 1018817-74-7
• Molecular Weight: 270.762
• Mol File: 1018817-74-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(3-chlorophenyl)-1-methyl-3-phenyl-4,5-dihydro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-chlorophenyl)-1-methyl-3-phenyl-4,5-dihydro-1H-pyrazole(1018817-74-7)
• EPA Substance Registry System: 5-(3-chlorophenyl)-1-methyl-3-phenyl-4,5-dihydro-1H-pyrazole(1018817-74-7)

Safety Data

• Hazardous Substances Data: 1018817-74-7(Hazardous Substances Data)

Upstream product

• 22966-13-8 3-(3-chlorophenyl)-1-phenylprop-2-en-1-one 
• 60-34-4 methylhydrazine 
• 22966-13-8 (2E)-3-(3-chlorophenyl)-1-phenylprop-2-en-1-one 
• 302-15-8 methylhydrazine sulfuric acid 

Downstream Products

• 67005-16-7 5-(3-chloro-phenyl)-1-methyl-3-phenyl-1H-pyrazole 

Relevant articles and documents

Design, synthesis, and in vitro hMAO-B inhibitory evaluation of some 1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazoles

A series of 1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazoles (3a-k and 4a-u) were designed, synthesized, and evaluated for their inhibitory efficacy towards the two hMAO isoforms. Most of the derivatives were found to be potent and selective hMAO-B inhibitors. In particular, derivative 3g showed greater hMAO-B affinity than selective inhibitor selegiline coupled with high selectivity index (SI = 145). The most selective hMAO-B inhibitor was the 3-methyl analogue 3f with an SI higher than 909.