101970-40-5

Basic information

• Product Name: Piperazine, 1-acetyl-4-(2-chloro-4-nitrophenyl)-
• CAS NO: 101970-40-5
• Molecular Formula: C12H14ClN3O3
• Molecular Weight: 283.714
• Mol File: 101970-40-5.mol

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-acetyl-4-(2-chloro-4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-acetyl-4-(2-chloro-4-nitrophenyl)-(101970-40-5)
• EPA Substance Registry System: Piperazine, 1-acetyl-4-(2-chloro-4-nitrophenyl)-(101970-40-5)

Safety Data

• Hazardous Substances Data: 101970-40-5(Hazardous Substances Data)

Upstream product

• 13889-98-0 N-acetylpiperidine 
• 350-30-1 3-chloro-4-fluoronitrobenzene 

Relevant articles and documents

Design, synthesis and SAR study of 2-aminopyrimidines with diverse Michael addition acceptors for chemically tuning the potency against EGFRL858R/T790M

The covalent binding nature of irreversible kinase inhibitors potentially increases the severity of “off-target” toxicity. Based on our continual strategy of chemically tuning the Michael addition acceptors, herein, we further explore the relationship amo

IMIDAZOLO-5-YL-2-ANILINOPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION

Compounds of the formula (I), wherein variable groups are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti cell proliferation) effect in a warm blooded animal, such as man.

Nucleophilic substitutions on 3-chloro-4-fluoronitrobenzene

Nucleophilic substitutions on 3-chloro-4-fluoronitrobenzene 5 with piperazines occur on the fluorine rather than on the chlorine atom as reported, to yield 3-chloro-4-piperazinylnitrobenzenes 8 and 9.