10203-32-4

Basic information

• Product Name: 4-DODECANOL
• Synonyms: 4-Hydroxydodecane;dodecan-4-ol;4-DODECANOL;n-Octyl-n-propylcarbinol;4-DODECANOL 99%;Dodecane-4-ol
• CAS NO: 10203-32-4
• Molecular Formula: C₁₂H₂₆O
• Molecular Weight: 186.33
• EINECS: 233-502-5
• Mol File: 10203-32-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 11-12°C
• Boiling Point: 130-132°C 19mm
• Flash Point: 130-132°C/19mm
• Appearance: /
• Density: 0,829 g/cm3
• Vapor Pressure: 0.00476mmHg at 25°C
• Refractive Index: 1.4400
• BRN: 1738597
• CAS DataBase Reference: 4-DODECANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-DODECANOL(10203-32-4)
• EPA Substance Registry System: 4-DODECANOL(10203-32-4)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 10203-32-4(Hazardous Substances Data)

Usage

General Description

4-Dodecanol, also known as lauryl alcohol, is a saturated fatty alcohol with the chemical formula C12H26O. It is a white, waxy solid at room temperature and is commonly used as an intermediate in the production of detergents, emulsifiers, and chemical intermediates. 4-Dodecanol also has potential applications in the manufacture of perfumes and flavorings due to its pleasant odor and taste. It is insoluble in water but soluble in organic solvents, and it is considered to have low toxicity. The compound is primarily derived from natural sources such as coconut oil and palm kernel oil, and it is generally recognized as safe for use in various consumer and industrial products.

InChI:InChI=1/C12H26O/c1-3-5-6-7-8-9-11-12(13)10-4-2/h12-13H,3-11H2,1-2H3

Upstream product

• 6137-26-4 dodecan-4-one 
• 629-27-6 1-Iodooctane 
• 123-72-8 butyraldehyde 
• 112-40-3 dodecane 
• 1471-21-2 4-octyl-1,3,2-dioxathiolane 2-oxide 
• 1119-86-4 1,2-decanediol 
• 872-05-9 1-Decene 
• 925-90-6 ethylmagnesium bromide 
• 117470-91-4 3-n-octyl-2,5-dioxathiolane 1,1-dioxide 
• 2386-64-3 ethylmagnesium chloride 
• 124-19-6 nonan-1-al 
• 628-91-1 di-n-propyl zinc 
• 111-66-0 oct-1-ene 
• 1825-65-6 butoxytrimethylsilane 

Downstream Products

• 2350-13-2 4-chloro-dodecane 
• 39789-28-1 Trimethyl-(1-propyl-nonyloxy)-silane 
• 6137-26-4 dodecan-4-one 

Relevant articles and documents

Preparation of Primary and Secondary Dialkylmagnesiums by a Radical I/Mg-Exchange Reaction Using sBu2Mg in Toluene

The treatment of primary or secondary alkyl iodides with sBu2Mg in toluene (25–40 °C, 2–4 h) provided dialkylmagnesiums that underwent various reactions with aldehydes, ketones, acid chlorides or allylic bromides. 3-Substituted secondary cyclohexyl iodides led to all-cis-3-cyclohexylmagnesium reagents under these exchange conditions in a highly stereoconvergent manner. Enantiomerically enriched 3-silyloxy-substituted secondary alkyl iodides gave after an exchange reaction with sBu2Mg stereodefined dialkylmagnesiums that after quenching with various electrophiles furnished various 1,3-stereodefined products including homo-aldol products (99 % dr and 98 % ee). Mechanistic studies confirmed a radical pathway for these new iodine/magnesium-exchange reactions.

Chemo- and Regioselective Functionalization of Polyols through Catalytic C(sp3)-C(sp3) Kumada-Type Coupling of Cyclic Sulfate Esters

This contribution describes a copper-catalyzed, C(sp3)-C(sp3) cross-coupling reaction of cyclic sulfate esters, a distinct class of electrophilic derivatives of polyols, with alkyl Grignard reagents to afford functionalized alcohol products in good yields. The method is operationally simple and highlights the potential of cyclic sulfate esters as highly reactive substrates in catalytic, chemoselective polyol transformations.