102036-29-3

Basic information

• Product Name: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
• Synonyms: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol;Protosappanin B;(7S,12aS)-7,8-Dihydro-7-(hydroxymethyl)-6H-dibenz[b,d]oxocin-3,7,10,11-tetrol
• CAS NO: 102036-29-3
• Molecular Formula: C₁₆H₁₆O₆
• Molecular Weight: 304.29500
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 102036-29-3.mol

Chemical Properties

• Boiling Point: 655.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.507
• Storage Temp.: 2-8°C
• PKA: 9.20±0.40(Predicted)
• CAS DataBase Reference: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol(102036-29-3)
• EPA Substance Registry System: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol(102036-29-3)

Safety Data

• Hazardous Substances Data: 102036-29-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Epicatechin is used as a therapeutic agent for its potential health benefits, particularly in the prevention and treatment of chronic diseases. Its antioxidant properties, along with its ability to support cardiovascular health, improve insulin sensitivity, and protect against oxidative stress, make it a valuable component in pharmaceutical formulations.
Used in Nutraceutical Industry:
In the nutraceutical industry, epicatechin is utilized as a dietary supplement to promote overall health and well-being. Its presence in various plant-based foods and its potential health benefits make it a popular ingredient in health supplements and functional foods.
Used in Cosmetic Industry:
Epicatechin is also used in the cosmetic industry for its antioxidant and anti-inflammatory properties. It can be incorporated into skincare products to protect the skin from oxidative damage and reduce inflammation, promoting a healthier and more youthful appearance.
Used in Food and Beverage Industry:
In the food and beverage industry, epicatechin is used as a natural antioxidant to extend the shelf life of products and improve their nutritional value. Its presence in various plant-based foods, such as tea, grapes, and cocoa, makes it a desirable ingredient for enhancing the health benefits of these products.
Used in Research and Development:
Epicatechin is extensively used in research and development for its potential therapeutic applications. Scientists are investigating its anti-inflammatory and neuroprotective effects, as well as its potential to prevent and treat various chronic diseases. This research aims to unlock the full potential of epicatechin and develop new treatments and interventions for various health conditions.

Upstream product

• 130233-78-2 protosappanin E 
• 111534-98-6 protosappanin C 
• 111830-78-5 C₁₉H₂₀O₆ 
• 111534-98-6 protosappanin C 

Relevant articles and documents

Homoisoflavonoids and Related Compounds. III. Phenolic Constituents of Caesalpinia japonica SIEB. et ZUCC.

A new homoisoflavonoid, 3'-deoxy-4-O-methylsappanol (3,7-dihydroxy-3-(4-hydroxybenzyl)-4-methoxychroman) was isolated from the wood of Caesalpinia japonica SIEB. et ZUCC. (Leguminosae), together with the known compounds, sappanol, episappanol, 4-O-methylsappanol, 4-O-methylepisappanol, sappanones A and B, sappanchalcone, 3-deoxysappanchalcone, isoliquiritigenin, butein, brazilin and protosappanins A, B and C.None of these compounds has previously been isolated from this plant.Keywords-Caesalpinia japonica; Leguminosae; wood; isolation; homoisoflavonoid; brazilin; dibenzoxocin derivative

Protosappanin C from Sappan Lignum and Absolute Configuration of Protosappanins

A new dibenzoxocin derivative, named protosappanin C (3), C16H14O6, amorphous powder, 23D -39.8 deg (MeOH), was isolated from Sappan Lignum (the dried heart-wood of Caesalpina sappan L. (Leguminosae)).It yielded sappanin (4) on alkaline fusion, an oxime (5), a dimethyl acetal (6) on treatment with p-toluenesulfonic acid in methanol, and protosappanin B (2) on reduction with sodium borohydride.The circular dichroism spectra of 3 and 6 indicated that their biphenyl system preferentially takes S configuration, from which R configuration was assigned to C-7 of 3.On the basis of the above chemical and spectroscopic evidence, the chemical structure of 3 was established as (7R)-7,8-dihydro-3,7,10,11-tetrahydroxy-7(6H)-dibenzoxocincarbaldehyde.A possible route of biosynthesis of protosappanins from sappanchalcone is discussed.Keywords - Leguminosae; Caesalpina sappan; Sappan Lignum; dibenzoxocin; biphenyl; protosappanin C; sappanin; stereochemistry

Homoisoflavonoids and Related Compounds. V. A Novel Dibenzoxocin Derivative from Caesalpinia sappan L.

A novel dibenzoxocin derivative, 7,8-dihydro-10-methoxy-3,7,11-trihydroxy-6H-dibenzoxocin-7-methanol was isolated from Sappan Lignum, the dried heartwood of Caesalpinia sappan L.The chemical structure was established on the basis of the spectrometric data and the chemical interrelation with protosappanin B (7,8-dihydro-3,7,10,11-tetrahydroxy-6H-dibenzoxocin-7-methanol).Keywords - Caesalpinia sappan; Sappan Lignum; Leguminosae; heartwood; dibenzoxocin derivative; 10-O-methylprotosappanin B; (1)H-(1)H difference NOE spectrum