102070-59-7Relevant articles and documents
New Synthetic Route to Spiroacetals. The 3,4-Dihydro-2H-pyran Approach to (+/-)-Talaromycin B
Kocienski, Philip,Yeates, Clive
, p. 1879 - 1884 (2007/10/02)
The nucleophylic cleavage of the oxirane (9) by the organocuprate derived from 3-ethyl-6-lithio-3,4-dihydro-2H-pyran (7) was the key step in a synthesis of racemic talaromycin B (12).A similar synthesis of desethyltalaromycin B (15) from (9) and 6-lithio-