1022993-40-3

Basic information

• Product Name: (+)-(S)-tetrahydrohinokiresinol
• Synonyms: (+)-(S)-tetrahydrohinokiresinol
• CAS NO: 1022993-40-3
• Molecular Weight: 256.345
• Mol File: 1022993-40-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-(S)-tetrahydrohinokiresinol(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(S)-tetrahydrohinokiresinol(1022993-40-3)
• EPA Substance Registry System: (+)-(S)-tetrahydrohinokiresinol(1022993-40-3)

Safety Data

• Hazardous Substances Data: 1022993-40-3(Hazardous Substances Data)

Upstream product

• 185020-38-6 (+)-Nyasol 
• 175520-27-1 (E)-4,4'-(3-ethenyl-1-propene-1,3-diyl)bisphenol 
• 17676-24-3 (-)-trans-Hinokiresinol 

Relevant articles and documents

Subunit composition of hinokiresinol synthase controls enantiomeric selectivity in hinokiresinol formation

Asparagus officinalis hinokiresinol synthase (HRS) is composed of two subunits, HRSα and HRSβ. Individually, each subunit forms (E)-hinokiresinol (EHR) from 4-coumaryl 4-coumarate, whereas a mixture of both subunits forms (Z)-hinokiresinol (ZHR) from the same substrate. In this study, we analyzed the enantiomeric compositions of ZHR and EHR formed after incubation of 4-coumaryl 4-coumarate with recombinant subunit proteins, recHRSα and/or recHRSβ, and with naturally occurring A. officinalis ZHR. The enantiomeric composition of ZHR formed by the mixture of recHRSα and recHRSβ was (+)-100% enantiomer excess (e.e.), identical to that of A. officinalis ZHR. In contrast, the enantiomeric compositions of EHR formed by recHRSα and recHRSβ, individually, were (-)-20.6 and (-)-9.0% e.e., respectively. These results clearly demonstrate that the subunit composition of A. officinalis HRS controls not only cis/trans isomerism but also enantioselectivity in hinokiresinol formation. The Royal Society of Chemistry.