1023276-78-9

Basic information

• Product Name: 8-cyclohexyl-2-{4-[2-(4-methyl-piperazin-1-yl)-ethyl]-phenylamino}-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
• Synonyms: 8-cyclohexyl-2-{4-[2-(4-methyl-piperazin-1-yl)-ethyl]-phenylamino}-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
• CAS NO: 1023276-78-9
• Molecular Weight: 518.659
• Mol File: 1023276-78-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-cyclohexyl-2-{4-[2-(4-methyl-piperazin-1-yl)-ethyl]-phenylamino}-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 8-cyclohexyl-2-{4-[2-(4-methyl-piperazin-1-yl)-ethyl]-phenylamino}-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester(1023276-78-9)
• EPA Substance Registry System: 8-cyclohexyl-2-{4-[2-(4-methyl-piperazin-1-yl)-ethyl]-phenylamino}-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester(1023276-78-9)

Safety Data

• Hazardous Substances Data: 1023276-78-9(Hazardous Substances Data)

Upstream product

• 262368-48-9 4-[2-(4-methylpiperazin-1-yl)-ethyl]-phenylamine 
• 928640-86-2 8-cyclohexyl-2-methanesulfonyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester 

Relevant articles and documents

5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE

The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a salt, stereoisomer, tautomer, crystalline, polymorph, amorphous, solvate, hydrate, ester, prodrug or metabolite form thereof, wherein A, Y, Z, R101 and R200 are described in the specification.