10261-94-6

Basic information

• Product Name: 3-Nitropyridine-2-Carbaldehyde
• Synonyms: 3-Nitropyridine-2-Carbaldehyde;3-Nitropyridine-2-carboxaldehyde;3-nitropicolinaldehyde;3-nitropyridin-2-carbaldehyde;3-Nitro-2-Pyridincarboxaldehyd;3-Nitro-2-pyridinecarboxaldehyde;3-Nitro-2-pyridinecarboxaldehyde 97%
• CAS NO: 10261-94-6
• Molecular Formula: C₆H₄N₂O₃
• Molecular Weight: 152.11
• Mol File: 10261-94-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 283.2 °C at 760 mmHg
• Flash Point: 125.1 °C
• Appearance: /
• Density: 1.432 g/cm³
• Vapor Pressure: 0.00321mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.20±0.10(Predicted)
• CAS DataBase Reference: 3-Nitropyridine-2-Carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nitropyridine-2-Carbaldehyde(10261-94-6)
• EPA Substance Registry System: 3-Nitropyridine-2-Carbaldehyde(10261-94-6)

Safety Data

• Hazardous Substances Data: 10261-94-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron, 54, p. 6311, 1998 DOI: 10.1016/S0040-4020(98)00328-7

InChI:InChI=1/C6H4N2O3/c9-4-5-6(8(10)11)2-1-3-7-5/h1-4H

Upstream product

• 67-56-1 methanol 
• 150281-83-7 2-ethenyl-3-nitropyridine 
• 931-19-1 2-methylpyridine N-oxide 
• 18699-87-1 2-methyl-3-nitropyridine 
• 131747-33-6 2-acetoxymethyl-4-nitropyridine 
• 5236-76-0 2-methyl-3-nitropyridine 1-oxide 
• 5470-18-8 2-Chloro-3-nitropyridine 
• 65156-92-5 (E)-N,N-dimethyl-2-(3-nitropyridin-2-yl)ethenamine 
• 36625-64-6 2-hydroxymethyl-4-nitropyridine 

Downstream Products

• 36625-67-9 3-nitropyridine-2-carboxaldehyde thiosemicarbazone 
• 108337-73-1 2-(N-Benzyl-N-methylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitro-2-pyridyl)-3,5-pyridinedicarboxylate 
• 1312605-70-1 2-(2-fluorophenyl)-1,5-naphthyridine-3-carbaldehyde 
• 1312605-71-2 1-(2-(2-fluorophenyl)-1,5-naphthyridin-3-yl)ethanol 
• 1312605-72-3 2-(1-(2-(2-fluorophenyl)-1,5-naphthyridin-3-yl)ethyl)-1H-isoindole-1,3 (2H)-dione 
• 1312605-73-4 1-(2-(2-fluorophenyl)-1,5-naphthyridin-3-yl)ethanamine 
• 1312606-13-5 C₁₅H₁₁FN₂O 

Relevant articles and documents

Synthesis and Properties of 3-, 4-, and 5-Nitro-2-pyridinecarbaldehyde 2-pyridylhydrazones and Characterization of Their Metal Complexes

Three hydrazones, 3-, 4-, and 5-nitro-2-pyridinecarbaldehyde 2-pyridylhydrazones, were synthesized.Their properties and reactivities with metal ions and the extraction and characteristics of the resultant complexes have been investigated and compared with one another.As a result, useful information on the molecular design of highly sensitive hydrazone reagents has been obtained.

HETEROCYCLIC COMPOUNDS AND THEIR USES

Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110δ activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia (T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.

PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

The present invention provides novel pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.