1027019-64-2Relevant articles and documents
Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics
Duffy, Kevin J.,Shaw, Anthony N.,Delorme, Evelyne,Dillon, Susan B.,Erickson-Miller, Connie,Giampa, Leslie,Huang, Yifang,Keenan, Richard M.,Lamb, Peter,Liu, Nannan,Miller, Stephen G.,Price, Alan T.,Rosen, Jon,Smith, Heather,Wiggall, Kenneth J.,Zhang, Lihua,Luengo, Juan I.
, p. 3573 - 3575 (2002)
High-throughput screening has resulted in the discovery of thiosemicarbazone thrombopoietin mimics. A shared pharmacophore hypothesis between this series and a previously identified class, the pyrazol-4-ylidenehydrazines, led to the rapid optimization of
