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1028268-32-7

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1028268-32-7 Usage

General Description

Diethyl 2-(4-chlorobenzamido)-2-[(2-oxo-1,2-dihydroquinolin-4-yl)methyl]malonate is a compound with a complex chemical structure. It contains amide, malonate, and quinoline groups. The presence of a chlorobenzamido group suggests that it is likely to have biological activity, possibly as a pharmaceutical or pesticide. Malonate is a versatile synthon in organic synthesis and can be used to form a variety of molecules. The quinoline group is often found in pharmaceuticals and is known to have various biological activities. Overall, the compound exhibits potential as a versatile building block for the synthesis of various biologically active compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 1028268-32-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,8,2,6 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1028268-32:
(9*1)+(8*0)+(7*2)+(6*8)+(5*2)+(4*6)+(3*8)+(2*3)+(1*2)=137
137 % 10 = 7
So 1028268-32-7 is a valid CAS Registry Number.

1028268-32-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Diethyl 2-(4-chlorobenzamido)-2-[(2-oxo-1,2-dihydroquinolin-4-yl)methyl]malonate

1.2 Other means of identification

Product number -
Other names Rebamipide intermediate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1028268-32-7 SDS

1028268-32-7Downstream Products

1028268-32-7Relevant articles and documents

Process for synthesizing rebamipide

-

Paragraph 0025; 0026; 0027, (2017/08/28)

The invention provides a process for synthesizing rebamipide. The process comprises the following steps: taking aminomalonic acid diethyl ester and 4-chlorobenzoyl chloride as raw material substrates so as to prepare an intermediate 4-chlorobenzoyl diethyl aminomalonate; reacting with 4-bromomethylcarbostyril so as to obtain 2-(4-chlorobenzhylamino)-2-ethoxycarbonyl-3-[2(1H)-quinolinone-4-yl] ethyl propionate; and finally, heating and refluxing in a sodium alcoholate solution, concentrating, and re-crystallizing, thereby obtaining the final product. The rebamipide prepared by the process disclosed by the method is high in yield, and the purity can reach 99.2%.

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