102841-46-3

Basic information

• Product Name: Moracin P
• Synonyms: Moracin P;5-[(6R)-6,7-Dihydro-6-hydroxy-7,7-dimethyl-5H-furo[3,2-g][1]benzopyran-2-yl]-1,3-benzenediol
• CAS NO: 102841-46-3
• Molecular Formula: C₁₉H₁₈O₅
• Molecular Weight: 326.34322
• Mol File: 102841-46-3.mol

Chemical Properties

• Boiling Point: 614.3°Cat760mmHg
• Flash Point: 325.3°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 5.99E-16mmHg at 25°C
• Refractive Index: 1.682
• PKA: 9.10±0.10(Predicted)
• CAS DataBase Reference: Moracin P(CAS DataBase Reference)
• NIST Chemistry Reference: Moracin P(102841-46-3)
• EPA Substance Registry System: Moracin P(102841-46-3)

Safety Data

• Hazardous Substances Data: 102841-46-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Moracin P is used as an anti-cancer agent for its potential to inhibit the growth of tumor cells. It may be employed in the development of treatments for various types of cancer due to its natural bioactive properties.
Used in Diabetes Management:
Moracin P is used as a regulatory agent for blood sugar levels and to improve insulin sensitivity, making it a potential candidate for the treatment and management of diabetes.
Used in Neurodegenerative Disease Treatment:
Moracin P is used as a neuroprotective agent due to its potential to protect neurons and possibly treat neurodegenerative diseases, offering a natural alternative for therapeutic intervention in such conditions.

InChI:InChI=1/C19H20O5/c1-19(2)18(22)7-11-3-10-6-15(23-16(10)9-17(11)24-19)12-4-13(20)8-14(21)5-12/h4-6,8-10,18,20-22H,3,7H2,1-2H3

Upstream product

• 102841-43-0 (9R)-moracin P 3'-O-α-L-arabinopyranoside 

Relevant articles and documents

Bioactive benzofuran derivatives from cortex mori radicis, and their neuroprotective and analgesic activities mediated by mGluR1

Four new benzofuran-type stilbene glycosides and 14 known compounds including 8 benzofuran-type stilbenes and 6 flavonoids were isolated from the traditional Chinese medicine, Cortex Mori Radicis. The new compounds were identified as (9R)-moracin P 3′-O-α-L-arabinopyranoside (1), (9R)-moracin P 9-O-β-D-glucopyranoside (2), (9R)-moracin P 3′-O-β-D-glucopyranoside (3), and (9R)-moracin O 10-O-β-D-glucopyranoside (4) based on the spectroscopic interpretation and chemical analysis. Three benzofuran-type stilbenes, moracin O (5), R (7), and P (8) showed significant neuroprotective activity against glutamate-induced cell death in SK-N-SH cells. In addition, moracin O (5) and P (8) also demonstrated a remarkable inhibition of the acetic acid-induced pain. The molecular docking with metabotropic glutamate receptor 1 (mGluR1) results indicated that these neuroprotective benzofuran-type stilbenes might be the active analgesic components of the genus Morus, and acted by mediating the mGluR1 pathway.