103055-07-8 Usage
Uses
Used in Agricultural Industry:
Lufenuron is used as a pesticide for the control of Lepidoptera and Coleoptera larvae on crops such as cotton, maize, and vegetables. It is also effective against citrus whitefly and rust mites on citrus fruit.
Used in Veterinary Medicine:
Lufenuron is used as an antiparasitic agent for controlling fleas on pets, such as cats and dogs. It helps in reducing flea larvae populations by preventing the hatching of eggs.
Used in Household Pest Control:
Lufenuron is used as an insecticide for controlling cockroaches in houses, providing an effective solution for pest management.
Flammability and Explosibility
Notclassified
Pharmacology
Antiparasitic. Lufenuron is a benzoylurea insecticide. This class of insecticides was previously used on fruits to decrease damage by insects. Lufenuron (Program) has been used for prevention of flea infections in dogs and cats because it inhibits chitin synthesis. For this use, it has been given to dogs at a dose of 10 mg/kg every 30 days and to cats at a dose of 30 mg/kg every 30 days. It may also have some inhibition on fungal cell membranes because it inhibits the cell wall of fungi, which contain chitin, and other complex polysaccharides. Because of this property on fungal cell membranes, there has been interest in using lufenuron to treat dermatophytes in small animals. However, proven efficacy has been controversial. Well-controlled studies have not confirmed consistent efficacy for treating dermatophytes in animals.
Veterinary Drugs and Treatments
Lufenuron is approved for use in dogs and cats 6 weeks of age and
older for the control of flea populations. The combination product
of lufenuron and milbemycin (Sentinel?) is indicated
for use
in puppies and dogs 4 weeks and older for prevention and control
flea populations, prevention
of heartworm disease, control of adult
hookworms, and the removal and control of adult roundworms
and whipworms.
Lufeneron showed initial promise as a treatment for fungal infections,
but the early enthusiasm has dampened considerably as
efficacy appears doubtful.
Metabolic pathway
Only limited information is available in the open literature on the
metabolism of lufenuron.
Degradation
Lufenuron is less stable at alkaline pH than under acidic conditions. The
DT50 at 25 °C is 160 days at pH 5,70 days at pH 7 and 32 days at pH 9
(PM).
Mode of action
Lufenuron has no systemic or translaminar effect. It is persistent with a transovarial effect. It may reduce the egg-Iaying rate or hinder the hatching process of embryos.
Check Digit Verification of cas no
The CAS Registry Mumber 103055-07-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,0,5 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 103055-07:
(8*1)+(7*0)+(6*3)+(5*0)+(4*5)+(3*5)+(2*0)+(1*7)=68
68 % 10 = 8
So 103055-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)
103055-07-8Relevant articles and documents
Method for exterminating termites
-
, (2008/06/13)
A method for exterminating termites comprising using an entomopathogenic nematode together with an inset-growth regulator or a slow-acting insecticide, wherein insecticidal effects are reinforced compared with the cases using singly the entomopathogenic nematode and the insect-growth regulator or the slow-acting insecticide, respectively, and a bait station for exterminating termites that contains an entomopathogenic nematode with an insect-growth regulator or a slow-acting insecticide. According to the invention, emission of harmful chemicals to environment can be suppressed. The invention is nonpoisonous for human being and livestock, and is useful for indoor or outdoor extermination of termites.
Insecticidal combination to control mammal fleas, in particular fleas on cats and dogs
-
, (2008/06/13)
Process and composition, in particular for controlling fleas on small mammals, characterized in that the composition includes, on the one hand, at least one insecticide of 1-N-arylpyrazole type, in particular fipronil, and, on the other hand, at least one compound of IGR (insect growth regulator) type, in doses and proportions which are parasiticidally effective on fleas, in a fluid vehicle which is acceptable for the animal and convenient for local application to the skin, preferably localized over a small surface area.
Method for the treatment of coccidioidomycosis in warm-blooded animals
-
, (2008/06/13)
This invention relates to the use of acyl urea compounds for the treatment or prophylaxis of Coccidioides immitis infections in warm-blooded animals. The invention has particular application in the treatment, prophylaxis or reduction of coccidioidomycosis.
