10314-52-0Relevant articles and documents
Synthesis of nor-ambreinolide from (+)-cis-abienol
Barrero, Alejandro F.,Sanchez, Juan F.,Alvarez-Manzaneda, Enrique J.,Altarejos, Joaquin,Munoz, Manuel,Haidour, Ali
, p. 6653 - 6662 (1994)
The synthesis of nor-ambreinolide (2) from cis-abienol (1) was carried out by direct treatment with OsO4-NaIO4 or RuO4-NaIO4. The oxymercuriation-demercuriation of 1 led to a mixture of 8,12-epoxylabdanes (5-17) which was also converted into nor-ambreinolide by treatment with RuO4-NaIO4. The formation pathways of such epoxy derivatives are discussed.