1036739-94-2

Basic information

• Product Name: C₂₆H₂₉N₃O₃
• Synonyms: C₂₆H₂₉N₃O₃
• CAS NO: 1036739-94-2
• Molecular Weight: 431.535
• Mol File: 1036739-94-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₉N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₉N₃O₃(1036739-94-2)
• EPA Substance Registry System: C₂₆H₂₉N₃O₃(1036739-94-2)

Safety Data

• Hazardous Substances Data: 1036739-94-2(Hazardous Substances Data)

Upstream product

• 169447-86-3 tert-butyl (S)-2-benzylpiperazine-1-carboxylate 
• 27810-64-6 isoquinoline-5-carboxylic acid 

Downstream Products

• 1036739-97-5 C₂₁H₂₁N₃O 

Relevant articles and documents

ROCK INHIBITORS AND USES THEREOF

The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are compounds that inhibit Rho - protein associated kinase function. Compounds of the invention include piperazinyl pyridines, piperazinylmethyl pyridines, piperazinyl ureas and carbamates, piperazinyl pyridines and quinoilines (including isoquinliones) as well as piperazinyl (including piperazinylmethyl) pyridines and quinolines (including isoquinolines). Compounds of the invention disrupt Rho-kinase activation and function and significantly inhibit tumor cell growth and induce tumor cell death.