10374-29-5Relevant articles and documents
One-Pot Synthesis of Enantioenriched β-Amino Secondary Amides via an Enantioselective [4+2] Cycloaddition Reaction of Vinyl Azides with N-Acyl Imines Catalyzed by a Chiral Br?nsted Acid
Chiba, Shunsuke,Kaga, Atsushi,Kikuchi, Jun,Nakanishi, Taishi,Terada, Masahiro
, (2020/06/25)
A catalytic enantioselective synthesis of β-amino secondary amides was achieved using vinyl azides as the enamine-type nucleophile and chiral N-Tf phosphoramide as the chiral Br?nsted acid catalyst through a five-step sequential transformation in one pot.
A new reactivity mode for the diazo group: Diastereoselective 1,3-aminoalkylation reaction of β-amino-α-diazoesters to give triazolines
Kuznetsov, Alexey,Gulevich, Anton V.,Wink, Donald J.,Gevorgyan, Vladimir
supporting information, p. 9021 - 9025 (2014/09/29)
A novel mode of reactivity for the diazo group, the 1,3-addition of a nucleophile and an electrophile to the diazo group, has been realized in the intramolecular aminoalkylation of β-amino-α-diazoesters to form tetrasubstituted 1,2,3-triazolines. The reaction exhibited a broad scope, good functional group tolerance, and excellent diastereoselectivity. In addition, a new Au-catalyzed intramolecular transannulation reaction of the obtained propargyl triazolines to give pyrroles has been discovered.
Modular synthesis of tetrasubstituted imidazoles and trisubstituted oxazoles by aldimine cross-coupling
Kison, Coralie,Opatz, Till
body text, p. 843 - 845 (2009/06/28)
A study was conducted to demonstrate the synthesis of tetrasubstituted imidazoles and trisubstituted oxazoles by aldimine cross-coupling reaction. The method involved 1,2-addition of easily available deprotonated N-monosubstituted α-aminotitriles to aldim
