10374-76-2

Basic information

• Product Name: 8-(methylsulfonylamino)quinoline
• Synonyms: 8-(methylsulfonylamino)quinoline;N-(8-quinolinyl)methanesulfonamide
• CAS NO: 10374-76-2
• Molecular Formula: C₁₀H₁₀N₂O₂S
• Molecular Weight: 222.26
• Mol File: 10374-76-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 143-144 °C
• Boiling Point: 405.9°C at 760 mmHg
• Flash Point: 199.3°C
• Appearance: /
• Density: 1.413g/cm³
• Vapor Pressure: 8.48E-07mmHg at 25°C
• Refractive Index: 1.676
• PKA: 6.45±0.30(Predicted)
• CAS DataBase Reference: 8-(methylsulfonylamino)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(methylsulfonylamino)quinoline(10374-76-2)
• EPA Substance Registry System: 8-(methylsulfonylamino)quinoline(10374-76-2)

Safety Data

• Hazardous Substances Data: 10374-76-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H10N2O2S/c1-15(13,14)12-9-6-2-4-8-5-3-7-11-10(8)9/h2-7,12H,1H3

Upstream product

• 607-35-2 8-nitroquinoline 
• 88-74-4 2-nitro-aniline 
• 578-66-5 8-amino quinoline 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1325206-88-9 N-(quinolin-8-yl)-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)methanesulfonamide 

Relevant articles and documents

Design and Synthesis of Heteroleptic Cyclometalated Iridium(III) Complexes Containing Quinoline-Type Ligands that Exhibit Dual Phosphorescence

The design and synthesis of some cyclometalated iridium(III) complexes containing quinoline-type ligands as ancillary ligands are reported. The emission spectra of Ir(III) complexes containing a quinolinolate (6, 8, 10) moiety exhibit a single emission pe

Sulfonamides and sulphonyl ester of quinolines as non-acidic, nonsteroidal, anti-inflammatory agents

Background: Quinolines are an important class of heterocyclic compounds possessing a wide range of biological activities. Previously, we had identified Schiff bases of quinoline as potential anti-inflammatory agents, thus the current work is the continuat

Visible Light-Promoted Photocatalytic C-5 Carboxylation of 8-Aminoquinoline Amides and Sulfonamides via a Single Electron Transfer Pathway

An efficient photocatalytic method was developed for the remote C5-H bond carboxylation of 8-aminoquinoline amide and sulfonamide derivatives. This methodology uses in situ generated ?CBr3 radical as a carboxylation agent with alcohol and is further extended to a variety of arenes and heteroarenes to synthesize the desired carboxylated product in moderate-to-good yields. The reaction proceeding through a single electron transfer pathway was established by a control experiment, and a butylated hydroxytoluene-trapped aryl radical cation intermediate in high-resolution mass spectrometry was identified.