103742-39-8

Basic information

• Product Name: methyl 5-amino-1-benzyl-1H-1,2,3-triazole-4-carboxylate
• Synonyms: methyl 5-amino-1-benzyl-1H-1,2,3-triazole-4-carboxylate;methyl 5-amino-1-benzyltriazole-4-carboxylate
• CAS NO: 103742-39-8
• Molecular Formula: C₁₁H₁₂N₄O₂
• Molecular Weight: 232.24
• Mol File: 103742-39-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 5-amino-1-benzyl-1H-1,2,3-triazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-amino-1-benzyl-1H-1,2,3-triazole-4-carboxylate(103742-39-8)
• EPA Substance Registry System: methyl 5-amino-1-benzyl-1H-1,2,3-triazole-4-carboxylate(103742-39-8)

Safety Data

• Hazardous Substances Data: 103742-39-8(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 372-09-8 cyanoacetic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 622-79-7 benzyl azide 
• 105-34-0 methyl 2-cyanoacetate 

Downstream Products

• 76003-76-4 1-benzyl-1H-[1,2,3]triazole-4-carboxylic acid methyl ester 
• 117534-78-8 (Z)-3-(5-Amino-1-benzyl-1H-[1,2,3]triazol-4-yl)-2-phenyl-acrylonitrile 
• 117534-76-6 5-Amino-3-benzyl-3H-[1,2,3]triazolo[4,5-b]pyridine-6-carbonitrile 
• 117534-77-7 3-Benzyl-5-oxo-4,5-dihydro-3H-[1,2,3]triazolo[4,5-b]pyridine-6-carbonitrile 
• 117534-75-5 3-Benzyl-5-methyl-3H-[1,2,3]triazolo[4,5-b]pyridine 
• 49789-96-0 5-amino-1-benzyl-1H-[1,2,3]triazole-4-carbaldehyde 

Relevant articles and documents

Flow hydrodediazoniation of aromatic heterocycles

Continuous flow processing was applied for the rapid replacement of an aromatic amino group with a hydride. The approach was applied to a range of aromatic heterocycles, confirming the wide scope and substituent-tolerance of the processes. Flow equipment was utilized and the process optimised to overcome the problematically-unstable intermediates that have restricted yields in previous studies relying on batch procedures. Various common organic solvents were investigated as potential hydride sources. The approach has allowed key structures, such as amino-pyrazoles and aminopyridines, to be deaminated in good yield using a purely organic-soluble system.