103747-88-2 Usage
General Description
1-(2,3-Dimethyl-3H-imidazol-4-yl)-ethanone is a chemical compound with a molecular formula C7H10N2O. It is a ketone derivative and belongs to the imidazole class of compounds. It is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds. Its structure contains a 3H-imidazol-4-yl moiety, which is a common pharmacophore in many medicinal compounds. The compound has potential applications in drug discovery and development due to its unique structure and diverse reactivity. Additionally, it may have biological activities or pharmaceutical properties that make it of interest in various research fields.
Check Digit Verification of cas no
The CAS Registry Mumber 103747-88-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,7,4 and 7 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 103747-88:
(8*1)+(7*0)+(6*3)+(5*7)+(4*4)+(3*7)+(2*8)+(1*8)=122
122 % 10 = 2
So 103747-88-2 is a valid CAS Registry Number.
103747-88-2Relevant articles and documents
Synthesis of 4(5)-Acyl-, 1-Substituted 5-Acyl, and 1-Substituted 4-Acyl-1H-imidazoles from 4-Aminoisoxazoles
Reiter, Lawrence A.
, p. 2714 - 2726 (2007/10/02)
4-Aminoisoxazoles can be acylated with a wide variety of activated carboxylic acids.Hydrogenation of the resulting amides gives α-(acylamino)enaminones, which cyclize to 4(5)-acylimidazoles upon treatment with base.This method allows for the synthesis of acylimidazoles with a wide range of substituents at C-2.Utilization of N-substituted 4-aminoisoxazoles in the same sequence of reactions yields 1-substituted 5-acylimidazoles, a substitution pattern not otherwise easily prepared.Treatment of α-(acylamino)enaminones, derived from N-unsubstituted isoxazoles, with primary amines leads to incorporation of the amine at the β-position with concomitant expulsion of ammonia.This sequence efficiently yields 1-substituted and 1,2-disubstituted 4-acylimidazoles but does not give satisfactory yields of 5-substituted 4-acylimidazoles due to steric inhibition of the amine exchange.