103999-81-1Relevant articles and documents
Elucidation of Racemization Process of Azaspirene Skeleton in Neutral Aqueous Media
Hirasawa, Shun,Mukai, Ken,Sakai, Shinnosuke,Wakamori, Shinnosuke,Hasegawa, Takahiro,Souma, Kazunori,Kanomata, Nobuhiro,Ogawa, Narihito,Aizawa, Mamoru,Emoto, Makoto
, p. 14457 - 14464 (2018)
Azaspirene and related congeners, which possess various biological activities, have a unique spirocyclic core structure. However, there are few studies on the chemical properties of (-)-azaspirene, despite the fact that it may provide important insights into unveiling the biosynthetic pathway. Here, we report a nine-step chemical synthesis of an azaspirene analogue with a new finding that the natural (-)-azaspirene skeleton easily racemizes in neutral aqueous media.
2-Isocyanato-2-alkensaeureester - Synthese und Reaktionen
Effenberger, Franz,Baumgartner, Christian,Kuehlwein, Juergen
, p. 1059 - 1061 (2007/10/02)
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