105168-92-1

Basic information

• Product Name: 4-NITRO-2-PROPOXY-PHENYLAMINE
• Synonyms: 4-NITRO-2-PROPOXY-PHENYLAMINE
• CAS NO: 105168-92-1
• Molecular Formula: C₉H₁₂N₂O₃
• Molecular Weight: 196.20318
• Mol File: 105168-92-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-NITRO-2-PROPOXY-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NITRO-2-PROPOXY-PHENYLAMINE(105168-92-1)
• EPA Substance Registry System: 4-NITRO-2-PROPOXY-PHENYLAMINE(105168-92-1)

Safety Data

• Hazardous Substances Data: 105168-92-1(Hazardous Substances Data)

Upstream product

• 55792-51-3 acetic acid-(2-propoxy-anilide) 
• 107-08-4 1-iodo-propane 
• 121-88-0 5-Nitro-2-aminophenol 

Downstream Products

• 105169-06-0 N-(4-Nitro-2-propoxy-phenyl)-acetamide 
• 105168-97-6 (1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl)-(4-nitro-2-propoxy-phenyl)-amine 
• 880145-98-2 N-(2-n-propyloxy-4-nitrophenyl)methanesulfonamide 
• 105169-08-2 N-(4-Amino-2-propoxy-phenyl)-acetamide 
• 105169-14-0 N⁴-(1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl)-2-propoxy-benzene-1,4-diamine 
• 105169-02-6 N¹-(1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl)-2-propoxy-benzene-1,4-diamine 
• 105169-11-7 N-[4-(1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-ylamino)-2-propoxy-phenyl]-acetamide 
• 105169-22-0 C₂₁H₂₃N₅O₇S 
• 105169-18-4 C₂₁H₂₃N₅O₇S 

Relevant articles and documents

Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer

Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[11C]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamide s ([11C]3a-f, alkyl

SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS

Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloakyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alk

Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition

Aromatase is a particularly attractive target in the treatment of estrogen receptor positive breast cancer. Aromatase levels in breast cancer cells are enhanced by prostaglandins and reduced by COX inhibitors. The synthesis and biological evaluation of a

Quinone Imine Route to Benzimidazol-2-ylcarbamates. Part 3. Effect of Extension of Conjugation in the Quinone Imine.

5-Aminobenzimidazol-2-ylcarbamates (11) and (17), in which the amine is linked to position 3 of 1,2-benzisothiazole 1,1-dioxide have been synthesised in good yields from the guanidines (10) and (16) by oxidative cyclisation.The cyclisation is regiospecific.It is likely that quinone imines with extended conjugation are intermediates in this reaction.