105604-23-7Relevant articles and documents
Zinc oxide catalyzed solvent-free mechanochemical route for C-S bond construction: A sustainable process
Md. Khaja Mohinuddin,Gangi Reddy
, p. 1207 - 1214 (2017/12/07)
A zinc oxide catalyzed solvent-free mechanochemical process has been developed for the rapid construction of C-S bonds by using a nucleophilic substitution reaction (SN2 mechanism) that involves a variety of thiols and phenacyl/ benzyl/alkyl bromides. Notable advantages of this method in-clude its broad substrate scope, clean reaction profile, safety, scalability, high product yields at ambient conditions, and the recyclability of the catalyst. Furthermore, the prepared compounds are valuable building blocks for the synthesis of various biologically active molecules.