1056629-32-3 Usage
General Description
3-Azaspiro[5.5]undecan-9-one, also known as Cisapride, is a chemical compound that is classified as a spiro compound, which is a type of heterocyclic compound containing a rigid backbone. It is widely used as a prokinetic agent, especially for treating gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD) and gastroparesis. Cisapride works by stimulating the muscles in the gastrointestinal tract, promoting the movement of food through the digestive system. However, it has been linked to several adverse effects, including cardiac arrhythmias and has been withdrawn from the market in many countries due to safety concerns. Despite its potential side effects, Cisapride continues to be researched for its therapeutic potential in various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1056629-32-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,6,6,2 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1056629-32:
(9*1)+(8*0)+(7*5)+(6*6)+(5*6)+(4*2)+(3*9)+(2*3)+(1*2)=153
153 % 10 = 3
So 1056629-32-3 is a valid CAS Registry Number.
1056629-32-3Relevant articles and documents
Pyrrolidine and thiazolidine compounds
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Page/Page column 10;11, (2008/06/13)
Compounds of formula (I): wherein: X1 represents an atom or group selected from CR4aR4b, O, S(O)q1 and NR5, wherein R4a, R4b, q1 and R5 are as defined in the description, m1 represents zero or an integer from 1 to 4 inclusive, m2 represents an integer from 1 to 4 inclusive, n1 and n2, which may be identical or different, each represent an integer from 1 to 3 inclusive, R1 represents hydrogen or a group selected from carboxy, alkoxycarbonyl, optionally substituted carbamoyl and optionally substituted alkyl, R2 represents hydrogen or alkyl, Ak represents an optionally substituted alkylene chain, p represents zero, 1 or 2, R3 represents hydrogen or cyano, X2 and X3, which may be identical or different, each represent either S(O)q2, or CR6aR6b, wherein q2, R6a and R6b are as defined in the description, its optical isomers, where they exist, and its addition salts with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful as DPP-IV inhibitors.
