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105679-22-9

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105679-22-9 Usage

General Description

7-Bromo-3,4-dihydro-2H-benzo[1,4]oxazine is a chemical compound with the molecular formula C8H7BrNO. It is a heterocyclic compound that contains a 7-bromo substitution on a 3,4-dihydro-2H-benzo[1,4]oxazine skeleton. 7-Bromo-3,4-dihydro-2H-benzo[1,4]oxazine is used in various chemical and pharmaceutical applications, including as a building block in the synthesis of other compounds. It may also have potential biological activities or pharmacological properties that make it of interest for further study. The compound's structure and properties make it a versatile and potentially valuable tool for chemical and pharmaceutical research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 105679-22-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,6,7 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 105679-22:
(8*1)+(7*0)+(6*5)+(5*6)+(4*7)+(3*9)+(2*2)+(1*2)=129
129 % 10 = 9
So 105679-22-9 is a valid CAS Registry Number.

105679-22-9 Well-known Company Product Price

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  • Alfa Aesar

  • (H61071)  7-Bromo-3,4-dihydro-2H-1,4-benzoxazine, 97%   

  • 105679-22-9

  • 250mg

  • 634.0CNY

  • Detail
  • Alfa Aesar

  • (H61071)  7-Bromo-3,4-dihydro-2H-1,4-benzoxazine, 97%   

  • 105679-22-9

  • 1g

  • 2031.0CNY

  • Detail

105679-22-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine

1.2 Other means of identification

Product number -
Other names 7-bromo-3,4-dihydro-2H-1,4-benzoxazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105679-22-9 SDS

105679-22-9Relevant articles and documents

INHIBITORS OF HIF PROLYL HYDROXYLASE

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Page/Page column 94, (2016/04/20)

The present invention concerns compounds of formula I or pharmaceutically acceptable salts thereof, which inhibit HIF prolyl hydroxylase, their use for enhancing endogenous production of erythropoietin, and for treating conditions associated with reduced endogenous production of erythropoietin such as anemia and like conditions, as well as pharmaceutical compositions comprising such a compound and a pharmaceutical carrier.

Achieving multi-isoform PI3K inhibition in a series of substituted 3,4-dihydro-2H-benzo[1,4]oxazines

Perry, Benjamin,Alexander, Rikki,Bennett, Gavin,Buckley, George,Ceska, Tom,Crabbe, Tom,Dale, Verity,Gowers, Lewis,Horsley, Helen,James, Lynwen,Jenkins, Kerry,Crepy, Karen,Kulisa, Claire,Lightfoot, Helen,Lock, Chris,Mack, Stephen,Morgan, Trevor,Nicolas, Anne-Lise,Pitt, Will,Sabin, Verity,Wright, Sara

scheme or table, p. 4700 - 4704 (2009/04/08)

The SAR and pharmacokinetic profiles of a series of multi-isoform PI3K inhibitors based on a 3,4-dihydro-2H-benzo[1,4]oxazine scaffold are disclosed.

Dihydro-benzo(1,4)oxazines

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Page/Page column 334, (2010/01/31)

The invention is directed to physiologically active compounds of formula (I): wherein R1represents R3—Z3—, R3—L2—R4—Z3—, R3—L3—Ar1—L4—Z3— or R3—L3—Ar1—L2—R4—Z3—; R2represents hydrogen, halogen, lower alkyl or lower alkoxy; A1represents a straight chain C2-3alkylene linkage optionally substituted by one or more groups chosen from alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, imino, oxo, thioxo, or alkyl substituted by —ZR6, —NY1Y2, —CO2R6or —C(═O)—NY1Y2; L1represents a direct bond; an alkenylene, alkylene, alkynylene, cycloalkenylene, cycloalkylene, heteroaryldiyl, heterocycloalkylene or arylene linkage each optionally substituted by (a) an acidic functional group, cyano, oxo, —S(O)mR9, R3, —C(═O)—R3, —C(═O)—OR3, —N(R8)—C(═O)—R9, —N(R8)—C(═O)—OR9, —N(R8)—SO2—R9, —NY4Y5or —[C(═O)—N(R10)—C(R5)(R11)]p—C(═O)—NY4Y5, or by (b) alkyl substituted by an acidic functional group, or by S(O)mR9, —C(═O)—NY4Y5or —NY4Y5; a —[C(═O)—N(R10)—C(R5)(R11)]p— linkage; a —Z2—R12— linkage; a —C(═O)—CH2—C(═O)— linkage; a —R12—Z2—R12— linkage; a —C(R4)(R13)—[C(═O)—N(R10)—C(R5)(R11)]p— linkage; or a —L5—L6—L7— linkage; Z1is NR17or O; Y is carboxy or an acid bioisostere; and the corresponding N-oxides, and their prodrugs; and pharmaceutically acceptable salts and solvates of such compounds and their N-oxides and prodrugs. Such compounds have valuable pharmaceutical properties, in particular the ability to regulate the interaction of VCAM-1 and fibronectin with the integrin VLA-4 (α4β1).

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