1056894-82-6

Basic information

• Product Name: 2,6-dimethyl-1-phenyl-1H-benzimidazole
• Synonyms: 2,6-dimethyl-1-phenyl-1H-benzimidazole
• CAS NO: 1056894-82-6
• Molecular Weight: 0
• Mol File: 1056894-82-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,6-dimethyl-1-phenyl-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-1-phenyl-1H-benzimidazole(1056894-82-6)
• EPA Substance Registry System: 2,6-dimethyl-1-phenyl-1H-benzimidazole(1056894-82-6)

Safety Data

• Hazardous Substances Data: 1056894-82-6(Hazardous Substances Data)

Usage

General Description

2,6-dimethyl-1-phenyl-1H-benzimidazole is a chemical compound with the molecular formula C15H14N2. It is a benzimidazole derivative and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. The compound has a bicyclic structure, with a benzene ring fused to an imidazole ring. It is a white to off-white solid and is slightly soluble in water but more soluble in organic solvents. 2,6-dimethyl-1-phenyl-1H-benzimidazole has been found to exhibit antifungal and antimicrobial properties, and is also used as a fluorescent indicator for cell imaging studies.

Upstream product

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Relevant articles and documents

Cobalt-catalyzed intramolecular C-N and C-O cross-coupling reactions: Synthesis of benzimidazoles and benzoxazoles

Cobalt(ii)-complex catalyzes efficiently the intramolecular C-N and C-O cross-couplings of Z-N′-(2-halophenyl)-N-phenylamidines and N-(2-bromophenyl)benzamides to afford the corresponding substituted benzimidazoles and benzoxazoles in the presence of K2CO3 at moderate temperature. The protocol is general, air stable and affords the products selectively in moderate to high yield.

Ligand-free copper-catalyzed synthesis of substituted benzimidazoles, 2-aminobenzimidazoles, 2-aminobenzothiazoles, and benzoxazoles

(Chemical Equation Presented) The synthesis of substituted benzimidazoles, 2-aminobenzimidazoles, 2-aminobenzothiazoles, and benzoxazoles is described via intramolecular cyclization of o-bromoaryl derivatives using copper(II) oxide nanoparticles in DMSO under air. The procedure is experimentally simple, general, efficient, and free from addition of external chelating ligands. It is a heterogeneous process and the copper(II) oxide nanoparticles can be recovered and recycled without loss of activity. 2009 American Chemical Society.