105730-97-0Relevant articles and documents
Molecular Self-Assembly of Bile Acid-Phospholipids Controls the Delivery of Doxorubicin and Mice Survivability
Sreekanth, Vedagopuram,Medatwal, Nihal,Pal, Sanjay,Kumar, Sandeep,Sengupta, Sagar,Bajaj, Avinash
, p. 2649 - 2659 (2017)
Lipid composition in general determines the drug encapsulation efficacy and release kinetics from liposomes that impact the clinical outcomes of cancer therapy. We synthesized three bile acid phospholipids by conjugating the phosphocholine headgroup to th
Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification
Mostarda, Serena,Passeri, Daniela,Carotti, Andrea,Cerra, Bruno,Colliva, Carolina,Benicchi, Tiziana,Macchiarulo, Antonio,Pellicciari, Roberto,Gioiello, Antimo
, p. 349 - 358 (2017/12/28)
Glucuronidation is considered an important detoxification pathway of bile acids especially in cholestatic conditions. Glucuronides are less toxic than the parent free forms and are more easily excreted in urine. However, the pathophysiological significanc
CATIONIC STEROID ANTIMICROBIAL DIAGNOSTIC, DETECTION, SCREENING AND IMAGING METHODS
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Page/Page column 85, (2010/04/27)
The invention relates to diagnostic, detection, screening and imaging methods. In various embodiments, methods of diagnosis, detection, screening and imaging include administering a cationic steroid antimicrobial or CSA to a subject having or at risk of having an infection or a hyperproliferative disorder (e.g., a tumor, cancer or neoplasia) in an amount effective to diagnose or detect the infection or the hyperproliferative disorder (e.g., a tumor, cancer or neoplasia) in the subject. In a particular aspect, a detectable CSA, namely CSA- 13 labeled with 99mTc is used to detect the presence of an infection.
