10574-69-3Relevant articles and documents
Aqueous microwave-assisted one-pot synthesis of N-substituted rhodanines
Nitsche, Christoph,Klein, Christian D.
, p. 5197 - 5201 (2012)
Two aqueous, one-pot, microwave-assisted methods for the rapid synthesis of N-substituted rhodanines from amine substrates are described. Alkyl- and benzylamines could be converted into the corresponding rhodanines with an atom-efficient one-pot, three-step protocol based on carbon disulfide and chloroacetic acid in short reaction times and good to excellent yields. An alternative, microwave-assisted one-pot, one-step protocol using bis(carboxymethyl)trithiocarbonate in water was developed for the synthesis of N-arylrhodanines from anilines.
HETEROCYCLIC INTEGRIN AGONISTS
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Paragraph 0285; 0286, (2018/07/29)
The present invention provides polycyclic oxothioxoimidazolidines, dioxoimidazolines, oxothioxooxazolidines, dioxooxazolidines, and related compounds, which are useful as integrin agonists. Methods for the treatment of integrin-mediated diseases such as cancer are also described.
Novel rhodanines with anticancer activity: Design, synthesis and CoMSIA study
Mandal, Subhankar P.,Mithuna,Garg, Aakriti,Sahetya, Sanjana S.,Nagendra,Sripad,Manjunath, Mendon Manisha,Sitaram,Soni, Mukesh,Baig, R. Nasir,Kumar, S. Vasanth,Kumar, B. R. Prashantha
, p. 58641 - 58653 (2016/07/06)
Three different series of some novel N-substituted rhodanines were designed for anticancer activity and prepared from the corresponding dithiocarbamates. The synthesized compounds were analyzed by IR, NMR and MASS to confirm their structures. All the titl