10575-97-0

Basic information

• Product Name: N-Nitroso-N-benzylacetamide
• Synonyms: N-Nitroso-N-benzylacetamide
• CAS NO: 10575-97-0
• Molecular Formula: C₉H₁₀N₂O₂
• Molecular Weight: 178.1879
• Mol File: 10575-97-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 276.4°Cat760mmHg
• Flash Point: 121°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 0.00481mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: N-Nitroso-N-benzylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Nitroso-N-benzylacetamide(10575-97-0)
• EPA Substance Registry System: N-Nitroso-N-benzylacetamide(10575-97-0)

Safety Data

• Hazardous Substances Data: 10575-97-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10N2O2/c1-8(12)11(10-13)7-9-5-3-2-4-6-9/h2-6H,7H2,1H3

Upstream product

• 80326-66-5 C₁₀H₁₀N₂O₂ 
• 85995-49-9 N-Nitroso-N-benzylformamide 
• 75-36-5 acetyl chloride 
• 588-46-5 N-(phenylmethyl)acetamide 

Downstream Products

• 4383-22-6 Allylbenzylamine 
• 27129-79-9 N-benzyl-N-nitroacetamide 
• 6907-68-2 N-[phenyl(acetylamino)methyl]acetamide 
• 101-81-5 Diphenylmethane 
• 140-11-4 Benzyl acetate 
• 620-47-3 1-methyl-3-(phenylmethyl)-benzene 
• 620-83-7 1-methyl-4-(phenylmethyl)benzene 
• 713-36-0 2-benzyltoluene 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 588-46-5 N-(phenylmethyl)acetamide 
• 43008-66-8 N-benzoyl-N-acetylbenzylamine 
• 539-30-0 1-(ethoxymethyl)benzene 
• 908094-04-2 phenyldiazomethane 
• 937-61-1 benzyl propyl ether 

Related news

Regular ArticleLabeling of the Active Site of α-Chymotrypsin with N-Nitroso-N-benzylacetamide (cas 10575-97-0) and Related-Compounds08/12/2019

α-Chymotrypsin (CT) is slowly inhibited by N-nitroso-N-benzylacetamide (1) at 25°C. The 13C-NMR spectrum of the hydrolysate of 13C-enriched 1-inhibited CT shows five new signals at 52.33, 44.55, 43.72, 36.79, and 32.90 ppm resulting from alkylation of the side chains and also of amide linkages...detailed

Relevant articles and documents

N-centered radicals in self-terminating radical cyclizations: Experimental and computational studies

(Chemical Equation Presented) Intermolecular addition of photochemically generated N-centered aminium and amidyl radicals 13a-d and 16a,b, respectively, to the cyclic alkyne 1 initiates a radical translocation/cyclization cascade, followed by an oxidative termination step that eventually leads to formation of the bicyclic ketones 7a and 8a. Computational studies were performed to gain insight into the mechanism of these reactions, which are an interesting modification of the recently discovered concept of self-terminating radical cyclizations.

Reaction of amides with nitric oxide (NO)

Amides were allowed to react with nitric oxide in aprotic and non- ethereal solvents to give the corresponding N-nitroso derivatives. The reaction was accelerated by addition of oxygen. The solvent effect revealed that the reaction did not proceed in the presence of protic media.

Reaction of N-Nitroso-N-benzylformamide with Phenylmagnesium Bromide and Phenyllithium

The action of aryl Grignard and lithium reagents on N-nitroso-N-benzylformamide (1) leads to products whose formation can be understood in terms of the intermediacy of benzyldiazotate ion.However, the presence of "hydrogen abstraction" products, e. g., anisole or naphthalene, coupled with the near absence of products traceable to the aldehyde moiety (expected from the attack at the formyl group) with 1 equiv of organometallics, suggests the initial formation of a complex.Possible rationalizations for the formation of the products are presented.