108791-97-5

Basic information

• Product Name: N-(4-amino-3-methylphenyl)methanesulfonamide(SALTDATA: FREE)
• Synonyms: N-(4-amino-3-methylphenyl)methanesulfonamide(SALTDATA: FREE);N-(4-aMino-3-Methylphenyl)MethanesulfonaMide;(4-amino-3-methylphenyl)methanesulfonamide
• CAS NO: 108791-97-5
• Molecular Formula: C₈H₁₂N₂O₂S
• Molecular Weight: 200.25808
• Mol File: 108791-97-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-amino-3-methylphenyl)methanesulfonamide(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-amino-3-methylphenyl)methanesulfonamide(SALTDATA: FREE)(108791-97-5)
• EPA Substance Registry System: N-(4-amino-3-methylphenyl)methanesulfonamide(SALTDATA: FREE)(108791-97-5)

Safety Data

• Hazardous Substances Data: 108791-97-5(Hazardous Substances Data)

Usage

General Description

N-(4-amino-3-methylphenyl)methanesulfonamide is a chemical compound commonly referred to as SALTDATA: FREE. It is an organic sulfonamide with the molecular formula C8H11N3O2S, and it is utilized in the pharmaceutical industry as a sulfonamide antibiotic. N-(4-amino-3-methylphenyl)methanesulfonamide(SALTDATA: FREE) exhibits antibacterial properties and is commonly used for the treatment of various bacterial infections. Additionally, it is known to inhibit the growth of certain strains of bacteria by interfering with the synthesis of dihydrofolic acid, a key precursor in the biosynthesis of purines and DNA. N-(4-amino-3-methylphenyl)methanesulfonamide is an important chemical in the development of antibiotic medications and is crucial in the fight against bacterial infections.

Upstream product

• 611-05-2 4-nitro-3-methylaniline 
• 108791-96-4 N-(3-methyl-4-nitrophenyl)methanesulfonamide 

Downstream Products

• 108792-00-3 4-dichloroacetamido-3-methyl-N-methanesulphonyl aniline 
• 108792-03-6 2,2-Dichloro-N-[4-[(E)-methanesulfonylimino]-2-methyl-cyclohexa-2,5-dien-(E)-ylidene]-acetamide 
• 108792-14-9 N-[4-[(E)-Methanesulfonylimino]-2-methyl-cyclohexa-2,5-dien-(E)-ylidene]-2,2-dimethyl-propionamide 
• 1208872-40-5 ethyl 3-(5-(5-bromothiophen-2-yl)-1-(2-methyl-4-(methylsulfonamido)phenyl)-1H-pyrrol-2-yl)propanoate 
• 1208872-35-8 C₂₁H₂₃BrN₂O₄S₂ 
• 1208872-37-0 C₂₅H₂₈N₄O₄S₂ 
• 108792-06-9 3-methyl-4-pivalamido-N-methanesulphonyl aniline 

Relevant articles and documents

COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF

The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.

QUINONE-IMIDES : REGIOSPECIFICITY OF NUCLEOPHILIC ATTACK ON N-ALKANESULPHONYL-N'-ALKANOYL 1,4-BENZOQUINONE-IMINES.

Substrates such as (2) undergo regiospecific attack by azide and thiocyanate ions at the terminus of the C=C-C=N-CO system.In the case of addition of azide, this is proved by the detailed analysis of the 1H and 13C NMR spectra of the products (11) derived from the quinone-imides (8).The structure of the products obtained by the addition of thiocyanate to the quinone-imides (10) and (20) is proved by their facile cyclisation to the 2-aminobenzothiazoles (18) and (21) respectively.