108994-74-7

Basic information

• Product Name: 2,7-Naphthyridine,3-methyl-(9CI)
• Synonyms: 2,7-Naphthyridine,3-methyl-(9CI)
• CAS NO: 108994-74-7
• Molecular Formula: C₉H₈N₂
• Molecular Weight: 144.17322
• Product Categories: PYRIDINE
• Mol File: 108994-74-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,7-Naphthyridine,3-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,7-Naphthyridine,3-methyl-(9CI)(108994-74-7)
• EPA Substance Registry System: 2,7-Naphthyridine,3-methyl-(9CI)(108994-74-7)

Safety Data

• Hazardous Substances Data: 108994-74-7(Hazardous Substances Data)

Usage

Structure

Heterocyclic organic compound with a naphthyridine structure

Functional Group

Methyl group attached to the third carbon of the ring

Derivative

Derived from the parent compound naphthyridine

Ring System

Contains a nitrogen-containing ring system

Potential Applications

Pharmaceuticals: Commonly used as building blocks for drug development
Materials Development: Potential applications in the development of dyes, pigments, and polymers

Versatility

Specific structure and properties may lend versatility in various industries

Research Opportunities

Further research and development could uncover additional uses and applications

Upstream product

• 80863-24-7 N-(4-pyridylmethylidene)tert-butylamine 
• 56752-28-4 N-(3-pyridylmethylidene)tert-butylamine 
• 67645-70-9 3,7-dimethyl-7H-[2,7]naphthyridin-1-one 
• 36106-39-5 3-methyl-2,7-naphthyridine-1(2H)-one 
• 56880-30-9 1-chloro-3-methyl-[2,7]naphthyridine 
• 112049-05-5 (3-methyl-[2,7]naphthyridin-1-yl)-hydrazine 

Downstream Products

• 114947-22-7 2-benzoyl-6-methyl-1,2,3,4-tetrahydro-[2,7]naphthyridine 
• 114947-20-5 2-benzoyl-3-methyl-1,2,3,4-tetrahydro-[2,7]naphthyridine 

Relevant articles and documents

Flash vacuum thermolysis of N-(3-and 4-Pyridylmethylidene)-tert- butylamines: Mechanisms of formation of pyrrolopyridines and naphthyridines

Pyrrolopyridines and naphthyridines are formed by flash vacuum thermolysis (FVT) of 3-and 4-pyridylmethylidene-tert-butylimines 8 and 15. Elimination of a methyl radical generates resonance stablized 2-azaallyl radicals a1 and b1. The formation of pyrrolopyridines 9, 16 and 17 is rationalized in terms of cyclization of 1-aziridinyl radicals a2 and b2. Formation of naphthyridine 10 from imine 8, and of 11 and 18 from imine 15, are in accord with cyclization of 1-azaallyl radicals a6 and b9. Formation of naphthyridine 11 from 8, and of 10 and 19 from 15, indicate the operation of the spiro-cyclization pathways forming intermediates a9 and b14. Formation of the 1,8-naphthyridine 20 (3%) indicates a rearrangement through aziridine b22 and biradical b23. DFT calculations at the CAM-B3LYP/6-311G(d,p) level support the proposed reaction mechanisms.