1092654-02-8Relevant articles and documents
Importance of molecular-level contacts under solventless conditions for chemical reactions and self-assembly
Orita, Akihiro,Okano, Junji,Uehara, Genta,Jiang, Lasheng,Otera, Junzo
, p. 1617 - 1623 (2007)
It has been shown that solventless reactions are accelerated when the reactants are mixed at molecular level. Accordingly, a solid film obtained by evaporating a solution of reactants mixture underwent facile reaction either upon grinding or upon simply standing. The effectiveness of these methods is evident from comparison with conventional solventless and solution reactions. It was concluded consequently that, once the molecular-level contacts are formed between reactants, the reaction occurs more efficiently under solventless conditions than in solution. Due to this pre-mixing method, efficient synthesis of [2]rotaxanes and rate acceleration of the Wittig reaction were achieved.