1092768-78-9

Basic information

• Product Name: C₂₆H₂₇ClN₂O₃
• CAS NO: 1092768-78-9
• Molecular Weight: 450.965
• Mol File: 1092768-78-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₇ClN₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₇ClN₂O₃(1092768-78-9)
• EPA Substance Registry System: C₂₆H₂₇ClN₂O₃(1092768-78-9)

Safety Data

• Hazardous Substances Data: 1092768-78-9(Hazardous Substances Data)

Upstream product

• 27810-64-6 isoquinoline-5-carboxylic acid 
• 1042591-87-6 C₁₆H₂₂ClNO₂ 

Relevant articles and documents

Small, non-peptide C5a receptor antagonists: Part 1

The optimisation of a series of amides for C5a receptor binding and functional activity, and physicochemical properties is described. The initial hit, 1 (IC50 1 μM), was discovered during high throughput screening, from which highly potent C5a receptor antagonists (e.g. 14, IC50 5 nM) were developed.