1093987-00-8Relevant articles and documents
Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups
Mahindra, Amit,Millard, Christopher J.,Black, Iona,Archibald, Lewis J.,Schwabe, John W. R.,Jamieson, Andrew G.
, p. 3178 - 3182 (2019)
Syntheses of Fmoc amino acids having zinc-binding groups were prepared and incorporated into substrate inhibitor H3K27 peptides using Fmoc/tBu solid-phase peptide synthesis (SPPS). Peptide 11, prepared using Fmoc-Asu(NHOtBu)-OH, is a
DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF
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Paragraph 0100; 0164; 0165, (2014/05/20)
Provided are crystalline α, α-disubstituted amino acids and their crystalline salts containing a terminal alkene on one of their side chains, as well as optionally crystalline halogenated and deuterated analogs of the α, α-disubstituted amino acids and their salts; methods of making these, and methods of using these.
Enantiospecific synthesis of 5-phenylpyrrolo[2,1-c][1,4]benzodiazepines
Legerén, Loreto,Gómez, Eduardo,Domínguez, Domingo
scheme or table, p. 7174 - 7177 (2009/04/10)
Enantiomerically pure 5-phenylpyrrolo[2,1-c][1,4]benzodiazepines were synthesized starting from 2-aminobenzophenones and 2-amino-4-methoxyxanthone, using l-proline as a chiral building block.
