109660-13-1

Basic information

• Product Name: 2-(4,4-DiMethyl-4,5-dihydro-2-oxazolyl)quinoline
• Synonyms: 2-(4,4-DiMethyl-4,5-dihydro-2-oxazolyl)quinoline;4,4-Dimethyl-2-(2-quinolinyl)oxazoline
• CAS NO: 109660-13-1
• Molecular Formula: C14H14N2O
• Molecular Weight: 226.27376
• Mol File: 109660-13-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 375.7±15.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• PKA: 3.27±0.61(Predicted)
• CAS DataBase Reference: 2-(4,4-DiMethyl-4,5-dihydro-2-oxazolyl)quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4,4-DiMethyl-4,5-dihydro-2-oxazolyl)quinoline(109660-13-1)
• EPA Substance Registry System: 2-(4,4-DiMethyl-4,5-dihydro-2-oxazolyl)quinoline(109660-13-1)

Safety Data

• Hazard Codes: Xn,N
• Statements: 21/22-36/38-51/53
• Safety Statements: 26-61
• Hazardous Substances Data: 109660-13-1(Hazardous Substances Data)

Upstream product

• 612-62-4 2-Chloroquinoline 
• 30093-99-3 4,4-dimethyl-2-oxazoline 
• 129665-83-4 Li(4,4-dimethyl-2-oxazolinyl) 
• 1150098-00-2 N-(1-hydroxy-2-methylpropan-2-yl)quinoline-2-carboxamide 
• 93-10-7 quinoline-2-carboxylic acid 

Relevant articles and documents

Copper-catalyzed benzylic oxidation of C(sp3)-H bonds

A selective oxidation of benzylic C(sp3)-H bonds to C(sp 3)-O bonds catalyzed by copper complexes of quinoline-imine ligands was developed with peresters as oxidants under mild reaction conditions, which converted benzylic methylenes directly into benzylic alcohols and esters by means of direct C-H bond functionalization.

A general and efficient catalyst system for a wacker-type oxidation using TBHP as the terminal oxidant: Application to classically challenging substrates

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MASKED MULTIFUNCTIONALIZATION OF AROMATICS BY PALLADIUM-CATALYZED HALOGEN-OXAZOLINE EXCHANGE

The (Ph3P)4Pd-catalyzed cross-coupling of aryl and heteroaryl halides with 2-(trimethylstannyl)-4,4-dimethyl-2-oxazoline 3 affords aromatic 2-oxazolines 6 in very high yields.