109745-15-5 Usage
Uses
Used in Peptide Synthesis:
FMOC-D-GLU-OTBU is used as a protected amino acid building block for the synthesis of peptides. The FMOC protecting group allows for the stepwise addition of amino acids in a controlled manner, while the OTBU group shields the carboxylic acid group, preventing unwanted side reactions during the synthesis process.
Used in Organic Chemistry Research:
FMOC-D-GLU-OTBU is used as a research compound in organic chemistry to study the properties and reactions of protected amino acids. The D configuration of the glutamic acid provides insights into the behavior of non-standard amino acid configurations in chemical reactions and their potential applications in the development of new pharmaceuticals and bioactive molecules.
Used in Pharmaceutical Development:
FMOC-D-GLU-OTBU is used as a precursor in the development of new pharmaceuticals, particularly in the synthesis of peptide-based drugs. FMOC-D-GLU-OTBU's protected groups enable the creation of complex peptide structures with specific biological activities, which can be further optimized for therapeutic applications.
Used in Biochemistry and Molecular Biology:
FMOC-D-GLU-OTBU is used as a tool in biochemical and molecular biology research to study protein structure, function, and interactions. FMOC-D-GLU-OTBU can be incorporated into peptides and proteins to investigate the effects of D-amino acids on protein folding, stability, and binding properties.
Check Digit Verification of cas no
The CAS Registry Mumber 109745-15-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,7,4 and 5 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 109745-15:
(8*1)+(7*0)+(6*9)+(5*7)+(4*4)+(3*5)+(2*1)+(1*5)=135
135 % 10 = 5
So 109745-15-5 is a valid CAS Registry Number.
InChI:InChI=1/C24H27NO6/c1-24(2,3)31-22(28)20(12-13-21(26)27)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,27)/t20-/m1/s1
109745-15-5Relevant articles and documents
Synthesis of cell-wall analogues of vancomycin-resistant Enterococci using solid phase peptide synthesis
Cho, Younghoon R.,Entress, Richard M. H.,Williams, Dudley H.
, p. 5229 - 5232 (1997)
A convenient method for the direct coupling of lithium D-lactate to 2-chlorotrityl chloride resin enabled the rapid and efficient solid phase synthesis of bacterial cell-wall precursor analogues (depsipeptides) found in vancomycin-resistant enterococci (VRE).
