1098782-64-9Relevant articles and documents
A three-component reaction between trialkyl phosphites or triphenylphosphine, dimethyl acetylenedicarboxylate and N-aryl-3- hydroxynaphthalene-2-carboxamide
Anary-Abbasinejad, Mohammad,Hassanabadi, Alireza,Mazraeh-Seffid, Manouchehr
, p. 708 - 712 (2008/09/20)
A three-component reaction between dimethyl acetylenedicarboxylate (DMAD) and trialkyl phosphites in the presence of N-aryl-3-hydroxynaphthalene-2- carboxamide leads to dialkyl 2-(dimethoxyphosphoryl)-3-[2-hydroxy-3- (arylcarbamyl)naphthalen-1-yl] succinate in excellent yields. A similar reaction with triphenylphosphine, instead of phosphites, produces dimethyl 2-[2-hydroxy-3-(arylcarbamoyl)naphthalen-1-yl]maleates. In the absence of triphenylphosphine or phosphite, DMAD adds to N-aryl-3-hydroxynaphthalene-2- carboxamide to produce alkyl 2-(alkoxycarbonylmethyl)-4-oxo-3-aryl-3,4-dihydro- 2H-naphtho[2,3-e][1,3]oxazine-2-carboxylates in good yields.