1098782-66-1

Basic information

• Product Name: diethyl 2-(ethoxycarbonylmethyl)-4-oxo-3-o-tolyl-3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazine-2-carboxylate
• CAS NO: 1098782-66-1
• Molecular Weight: 447.488
• Mol File: 1098782-66-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl 2-(ethoxycarbonylmethyl)-4-oxo-3-o-tolyl-3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(ethoxycarbonylmethyl)-4-oxo-3-o-tolyl-3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazine-2-carboxylate(1098782-66-1)
• EPA Substance Registry System: diethyl 2-(ethoxycarbonylmethyl)-4-oxo-3-o-tolyl-3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazine-2-carboxylate(1098782-66-1)

Safety Data

• Hazardous Substances Data: 1098782-66-1(Hazardous Substances Data)

Upstream product

• 135-61-5 naphthol ASD 
• 762-21-0 acetylenedicarboxylic acid diethyl ester 

Relevant articles and documents

A three-component reaction between trialkyl phosphites or triphenylphosphine, dimethyl acetylenedicarboxylate and N-aryl-3- hydroxynaphthalene-2-carboxamide

A three-component reaction between dimethyl acetylenedicarboxylate (DMAD) and trialkyl phosphites in the presence of N-aryl-3-hydroxynaphthalene-2- carboxamide leads to dialkyl 2-(dimethoxyphosphoryl)-3-[2-hydroxy-3- (arylcarbamyl)naphthalen-1-yl] succinate in excellent yields. A similar reaction with triphenylphosphine, instead of phosphites, produces dimethyl 2-[2-hydroxy-3-(arylcarbamoyl)naphthalen-1-yl]maleates. In the absence of triphenylphosphine or phosphite, DMAD adds to N-aryl-3-hydroxynaphthalene-2- carboxamide to produce alkyl 2-(alkoxycarbonylmethyl)-4-oxo-3-aryl-3,4-dihydro- 2H-naphtho[2,3-e][1,3]oxazine-2-carboxylates in good yields.