1100598-48-8

Basic information

• Product Name: BenzeneMethanol, 3-[5-[(1-Methyl-4-piperidinyl)Methoxy]-2-pyriMidinyl]-
• Synonyms: BenzeneMethanol, 3-[5-[(1-Methyl-4-piperidinyl)Methoxy]-2-pyriMidinyl]-;BenzeneMethanol, 3-[5-[(1...;(3-(5-((1-Methylpiperidin-4-yl)methoxy)pyrimidin-2-yl)phenyl)methanol;3-[5-[(1-Methyl-4-piperidinyl)methoxy]-2-pyrimidinyl]-Benzenemethanol
• CAS NO: 1100598-48-8
• Molecular Formula: C₁₈H₂₃N₃O₂
• Molecular Weight: 313.39412
• Mol File: 1100598-48-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 420.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.149±0.06 g/cm3(Predicted)
• PKA: 14.04±0.10(Predicted)
• CAS DataBase Reference: BenzeneMethanol, 3-[5-[(1-Methyl-4-piperidinyl)Methoxy]-2-pyriMidinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzeneMethanol, 3-[5-[(1-Methyl-4-piperidinyl)Methoxy]-2-pyriMidinyl]-(1100598-48-8)
• EPA Substance Registry System: BenzeneMethanol, 3-[5-[(1-Methyl-4-piperidinyl)Methoxy]-2-pyriMidinyl]-(1100598-48-8)

Safety Data

• Hazardous Substances Data: 1100598-48-8(Hazardous Substances Data)

Usage

General Description

BenzeneMethanol, 3-[5-[(1-Methyl-4-piperidinyl)Methoxy]-2-pyriMidinyl]- is a chemical compound with a complex molecular structure that includes benzene, methanol, and pyrimidine. It is also known by the trade name TAK-632 and is used in scientific research as a potential inhibitor of cancer cell growth. BenzeneMethanol, 3-[5-[(1-Methyl-4-piperidinyl)Methoxy]-2-pyriMidinyl]- has attracted interest as a potential anti-cancer drug due to its ability to target specific cellular pathways involved in cancer progression. It has also been studied for its potential application in the treatment of other diseases such as Alzheimer's and Parkinson's. However, further research is needed to fully understand its potential therapeutic benefits and side effects.

Upstream product

• 1100598-47-7 4-[2-(3-methoxycarbonyl-phenyl)-pyrimidin-5-yloxymethyl]-piperidine-1-carbonic acid tert-butylester 

Downstream Products

• 1100598-32-0 (3-(1-(3-(5-(1-methylpiperidin-4-ylmethoxy)pyrimidin-2-yl)benzyl)-1,6-dihydro-6-oxopyridazin-3-yl)benzonitrile) 

Relevant articles and documents

NOVEL POLYMORPHIC FORMS OF 3-(1-{3-[5-(1-METHYL-PIPERIDIN-4YLMETHOXY)-PYRIMIDIN-2-YL]-BENZYL}-6-OXO-1,6-DIHYDRO-PYRIDAZIN-3-YL)-BENZONITRILE HYDROCHLORIDE SALT AND PROCESSES OF MANUFACTURING THEREOF

The present invention relates to hydrochloride solvates of 3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer.