111468-90-7Relevant articles and documents
3,6,13,16-Tetrapropylporphycene: Rational Synthesis, Complexation, and Halogenation
Nagamaiah, Jodukathula,Dutta, Arnab,Pati, Narendra Nath,Sahoo, Sameeta,Soman, Rahul,Panda, Pradeepta K.
, p. 2721 - 2729 (2022/02/05)
We have designed and synthesized 3,6,13,16-tetrapropylporphycene for the first time as its alkyl analogue from ethyl 4-propyl-1H-pyrrole-2-carboxylate. The substituent effect was found to be more intense than reported positional isomeric tetrapropylporphycenes. The freebase porphycene exhibited moderate fluorescence and complexation ability with divalent metal ions, including Zn(II), which displayed an enhanced emission quantum yield (~30%). The Pd(II) complex and freebase β-tetrabromoporphycene generated singlet oxygen efficiently (75 and 51%, respectively) and, hence, may find application as potential photosensitizers in photodynamic therapy.
Selective inhibitors of ERK protein kinase and uses thereof
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Page/Page column 22-23, (2008/06/13)
Described herein are compounds that are useful as ERK2 inhibitors. These compounds, and pharmaceutically acceptable compositions thereof, are useful for treating or lessening the severity of a variety of disorders, including proliferative disorders such a
Heterocyclic inhibitors of ERK2 and uses thereof
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, (2008/06/13)
Described herein are compounds that are useful as protein kinase inhibitors having the formula: wherein Z1 and Z2 are each independently nitrogen or CH and Ring A, TmR1, QR2, UnR3/sup