112-10-7Relevant articles and documents
Catalytic transfer hydrogenation of oleic acid to octadecanol over magnetic recoverable cobalt catalysts
Wang, Juncheng,Nie, Renfeng,Xu, Ling,Lyu, Xilei,Lu, Xiuyang
supporting information, p. 314 - 320 (2019/01/28)
Efficient transformation of biomass into fuel and chemicals under mild conditions with cost-effective and environmentally friendly characters is highly desirable but still challenging. Herein, a scalable and Earth-abundant cobalt catalyst was used for selective catalytic transfer hydrogenation (CTH) of unsaturated fatty acids to fatty alcohols with sustainable isopropanol as a hydrogen donor. By tuning the surface Co composition by varying the reduction temperature, the catalytic performance could be easily boosted. At 200 °C in 4 h, the optimal catalyst Co-350 (reduced at 350 °C) gives 100% oleic acid conversion with 91.9% octadecanol selectivity. Various characterization studies reveal that the co-existence of Coδ+ and Co0 over the cobalt core might be responsible for its high performance for CTH of oleic acid. This catalyst could be magnetically separated and is highly stable for reusing ten times. Moreover, this cobalt catalyst is relatively cheap and easy to scale-up, thus achieving a low-cost transformation of biomass into high value-added chemicals.
Efficient microwave-assisted esterification reaction employing methanesulfonic acid supported on alumina as catalyst
Fabian, Lucas,Gomez, Matias,Kuran, Juan A. Caturelli,Moltrasio, Graciela,Moglioni, Albertina
, p. 2386 - 2392 (2014/07/22)
A rapid and efficient protocol assisted by microwave irradiation for the synthesis of esters using methanesulfonic acid (CH3SO3H) supported on Al2O3 (AMA) as catalyst and free of solvent is described. The products were obtained in good yields and purity, with reduced reaction time, and the process is simple and environmentally benign. Copyright
Synthesis and evaluation of different fatty acid esters formulated into Precirol ATO-based lipid nanoparticles as vehicles for topical delivery
Sanna, Vanna,Mariani, Alberto,Caria, Giuseppe,Sechi, Mario
experimental part, p. 680 - 684 (2009/12/26)
A series of isopropyl fatty esters having different chain length (C 13-C23) were synthesized and formulated in lipid nanoparticles based on Precirol ATO to evaluate their effect on the physicochemical properties of these latter. Moreover, drug loading and skin permeation of Econazole nitrate, chosen as a lipophilic model drug, were evaluated as well. The obtained nanosystems, prepared by high shear homogenization method, had a mean diameter ranging from 180 to 280 nm and showed an encapsulation efficiency of about 100%. Ex vivo permeation results demonstrated a parabolic correlation between permeation effect and chain length of the fatty esters present in the lipid nanoparticles formulated in hydrophilic gels. The maximum flux of drug was observed for the nanoparticles containing esters with 17 and 19 carbon atoms, suggesting that these formulations may constitute a potential carrier for topical delivery of econazole nitrate.
