112-32-3

Basic information

• Product Name: n-Octyl formate
• Synonyms: Octylalcohol, formate (6CI); 1-Octyl formate; NSC 404473; Octyl formate; n-Octylformate
• CAS NO: 112-32-3
• Molecular Formula: C₉H₁₈O₂
• Molecular Weight: 158.27
• EINECS: 203-959-5
• Mol File: 112-32-3.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 199.6°Cat760mmHg
• Flash Point: 77.2°C
• Appearance: /
• Density: 0.875g/cm³
• Vapor Pressure: 0.339mmHg at 25°C
• Refractive Index: 1.419
• CAS DataBase Reference: n-Octyl formate(CAS DataBase Reference)
• NIST Chemistry Reference: n-Octyl formate(112-32-3)
• EPA Substance Registry System: n-Octyl formate(112-32-3)

Safety Data

• Hazardous Substances Data: 112-32-3(Hazardous Substances Data)

Usage

General Description

n-Octyl formate is a chemical compound with the formula C9H18O2. It is an ester derived from formic acid and n-octanol. This colorless liquid is commonly used as a flavoring agent in the food industry, providing a fruity and sweet aroma. It is also used in the production of perfumes and fragrances. Additionally, n-octyl formate is used as a solvent in various industries and as a reagent in organic synthesis. It is important to note that n-octyl formate should be handled with caution, as it can irritate the skin and respiratory system upon exposure.

InChI:InChI=1/C9H18O2/c1-2-3-4-5-6-7-8-11-9-10/h9H,2-8H2,1H3

Upstream product

• 111-87-5 octanol 
• 77287-34-4 formamide 
• 111-85-3 n-chlorooctane 
• 111-83-1 1-bromo-octane 
• 3386-35-4 1-octyl p-toluenesulfonate 
• 68-12-2 N,N-dimethyl-formamide 
• 646-06-0 1,3-DIOXOLANE 
• 592-41-6 1-hexene 
• 74-85-1 ethene 
• 123-39-7 N-Methylformamide 
• 629-27-6 1-Iodooctane 
• 89781-11-3 potassium 2-naphthalenethiolate 
• 124-38-9 carbon dioxide 
• 141-53-7 sodium formate 

Downstream Products

• 111-65-9 octane 
• 111-87-5 octanol 
• 56425-00-4 dimethyl 2-octylsuccinate 
• 76086-32-3 2-(7-Formyloxy-1-methyl-heptyl)-succinic acid dimethyl ester 
• 76086-33-4 2-(1-Ethyl-6-formyloxy-hexyl)-succinic acid dimethyl ester 
• 133788-00-8 6-phenyl-3a,4-dihydro-1H-cyclopenta[c]furan-5(3H)-one 

Relevant articles and documents

Catalyst Poisoning Phenomenon in Phase Transfer Catalysis: Effect of Aqueous Phase Concentration

Catalyst poisoning was studied in the phase transfer-catalysed esterification of alkyl chlorides by sodium formate; the poisoning effect is minimized by use of highly concentrated formate solutions where high conversion and first order kinetics are observed.

Lipase-catalyzed transesterification of ethyl formate to octyl formate

The preparation of octyl formate via lipase-catalyzed transesterification of ethyl formate with 1-octanol is demonstrated. To shift the equilibrium of the reaction, ethyl formate was added in surplus but could be partially recovered for subsequent reactions. The same was true for the biocatalyst (Novo435), which could be reused at least 27 times. This method gives simple access to a hydrophobic formic acid ester, which can be used as a reactive organic phase in biocatalytic redox reactions. The enzymatically prepared octyl formate can be utilized by formate dehydrogenase to regenerate NADH from NAD+.

Method for preparing formate-type compound

The invention discloses a method for preparing a formate-type compound. The method comprises the following steps of: adopting an alcohol-type compound and 1,3-dihydroxyacetone as reaction raw materials, and under the existence of a composite catalyst and an oxidant, reacting for 2-48 hours in a reaction medium in a reactor at a reaction temperature of 25-100 DEG C so as to obtain the formate-typecompound. The method disclosed by the invention is simple, and is mild in reaction condition, and by the method, a target product can be obtained by low cost and high yield; the used catalyst has highcatalytic activity, and is easily separated from a reaction system to be repeatedly used; the whole process is environment-friendly, and the reaction raw material (1,3-dihydroxyacetone) is easily converted from a side product (glycerol) of biodiesel, so that the utilization of the glycerol is promoted.

Deep eutectic solvent choline chloride·2CrCl3·6H2O: An efficient catalyst for esterification of formic and acetic acid at room temperature

A highly efficient and selective method for esterification of formic and acetic acid with alcohols has been achieved at room temperature, with the choline chloride (ChCl)/chromium(iii) chloride hexahydrate (CrCl3·6H2O) deep eutectic solvent as a catalyst. High yields and good selectivities of organic esters are obtained using DES [ChCl][CrCl3·6H2O]2 with the molar ratio 5:1 (carboxylic acids:alcohols) at room temperature in 24 h. The ease of recovery and reusability of DES with high catalytic activity makes this method efficient and practical.