1123-40-6

Basic information

• Product Name: 3,3-DIMETHYLGLUTARIMIDE
• Synonyms: BETA-BETA-DIMETHYL GLUTARIMIDE;3,3-DIMETHYLGLUTARIMIDE;4,4-DIMETHYLPIPERIDINE-2,6-DIONE;4,4-DIMETHYL-2,6-PIPERIDINEDIONE;3,3-dimethyl-glutarimid;Glutarimide, 3,3-dimethyl-;3,3-Dimethylglutarimide,99%;3,3-DiMethylglutariMide, 99% 25GR
• CAS NO: 1123-40-6
• Molecular Formula: C₇H₁₁NO₂
• Molecular Weight: 141.17
• EINECS: 214-373-4
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Piperidines
• Mol File: 1123-40-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 144-146 °C(lit.)
• Boiling Point: 258.21°C (rough estimate)
• Flash Point: 125.3 °C
• Appearance: white to white-grey crystalline powder
• Density: 1.1522 (rough estimate)
• Vapor Pressure: 0.0079mmHg at 25°C
• Refractive Index: 1.5026 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 11.81±0.40(Predicted)
• Water Solubility: Soluble in water.
• BRN: 111981
• CAS DataBase Reference: 3,3-DIMETHYLGLUTARIMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DIMETHYLGLUTARIMIDE(1123-40-6)
• EPA Substance Registry System: 3,3-DIMETHYLGLUTARIMIDE(1123-40-6)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38-43
• Safety Statements: 26-36/37-22
• RIDADR: 2811
• WGK Germany: 2
• RTECS: MA4348000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 1123-40-6(Hazardous Substances Data)

Usage

Chemical Properties

white to white-grey crystalline powder

Uses

3,3'-dimethylglutarimide were used as the barbital subsitutes. 3,3-di-methyl-glutarimide is involved formation of the heterodimer.

Purification Methods

Recrystallise the imide from hot H2O or EtOH [Arnett & Harrelson J Am Chem Soc 109 809 1987]. [Beilstein 21 H 391, 21 I 331, 21 II 309, 21 III/IV 4601, 21/9 V 592.]

InChI:InChI=1/C7H11NO2/c1-7(2)3-5(9)8-6(10)4-7/h3-4H2,1-2H3,(H,8,9,10)

Upstream product

• 4160-82-1 3,3-dimethylglutaric anhydride 
• 77287-34-4 formamide 
• 57-13-6 urea 
• 6630-38-2 5-cyano-2-imino-4,4-dimethyl-6-oxo-piperidine-3-carboxylic acid amide 
• 871901-54-1 5-cyano-4,4-dimethyl-2,6-dioxo-piperidine-3-carboxylic acid 
• 38597-82-9 4,4-dimethyl-6-acetonylpiperid-2-one 
• 66393-63-3 N-bromo-3,3-dimethylglutarimide 
• 4839-46-7 3,3-Dimethylglutaric acid 
• 274690-12-9 2-cyano-3,3-dimethyl-glutaric acid diethyl ester 
• 77406-71-4 2-cyano-3,3-dimethyl-glutaric acid-5-ethyl ester 
• 854704-89-5 4,4-dimethyl-2,6-dioxo-piperidine-3-carbonitrile 

Downstream Products

• 4045-30-1 4,4-dimethylpiperidine 
• 55047-81-9 4,4-dimethylpiperidin-2-one 
• 4839-46-7 3,3-Dimethylglutaric acid 
• 38646-68-3 4,4-dimethylpiperidine hydrochloric acid salt 
• 25115-67-7 N,3,3-trimethylglutarimide 
• 142336-22-9 Mesmar 
• 83928-76-1 gepirone 
• 158890-30-3 2-chloro-1-(4,4-dimethylpiperidin-1-yl)-ethanone 
• 1350473-57-2 (Z)-1-benzyl-3-(hydroxyimino)-4,4-dimethylpiperidine-2,6-dione 

Related news

Vibrational spectra and normal coordinate analysis of 3,3-DIMETHYLGLUTARIMIDE (cas 1123-40-6) and its mercury(II) complex09/24/2019

FT-Raman and FT-IR spectra are reported for 3,3-dimethylglutarimide, its N-deuterated derivative and the Hg(II) complex with 3,3-dimethylglutarimidate ion, Hg(C7H10NO2)2·H2O. A complete vibrational assignments are given for all internal vibrations of the molecules and are supported by normal co...detailed

Relevant articles and documents

Spin state modulation of iron spin crossover complexes via hydrogen-bonding self-assembly

Iron complexes derived from 6-diaminotriazyl-2,2′-bipyridines display spin crossover behaviour, and hydrogen bonding-controlled self-assembly with a suitable barbiturate partner can modulate the crossover from mixed low and high spin to high spin. This system is the first to use solution-phase self-assembly of complementary hydrogen-bonding organic species to modulate spin state.

Spin state modulation of iron spin crossover complexes via hydrogen-bonding self-assembly

Iron complexes derived from 6-diaminotriazyl-2,2′-bipyridines display spin crossover behaviour, and hydrogen bonding-controlled self-assembly with a suitable barbiturate partner can modulate the crossover from mixed low and high spin to high spin. This system is the first to use solution-phase self-assembly of complementary hydrogen-bonding organic species to modulate spin state.

SYNTHESIS AND PROPERTIES OF 4,4-DIMETHYLCONIINE DERIVATIVES

In the course of transformations of 4,4-dimethyl-6-acetonylpiperid-2-one, a series of 4,4-dimethylconiine derivatives exhibiting an influence on the arterial blood-pressure was synthesized.The structure of new compounds was established on the basis of spectral data and chemical reactions leading finally to known 4,4-dimethylpiperid-2,6-dione.