112302-89-3Relevant articles and documents
An umpolung-enabled copper-catalysed regioselective hydroamination approach to α-amino acids
Hirano, Koji,Miura, Masahiro,Nishino, Soshi
, p. 11525 - 11537 (2021)
A copper-catalysed regio- and stereoselective hydroamination of acrylates with hydrosilanes and hydroxylamines has been developed to afford the corresponding α-amino acids in good yields. The key to regioselectivity control is the use of hydroxylamine as
Copper-catalyzed amination of ketene silyl acetals with hydroxylamines: Electrophilic amination approach to α-amino acids
Matsuda, Naoki,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro
, p. 11827 - 11831 (2013/01/15)
Role reversal: The title reaction has been developed to deliver α-amino acids under very mild reaction conditions (see scheme; dpppen=1,5-bis(diphenylphosphino)pentane). The catalysis provides a new C-N bond-forming approach for the synthesis of α-amino a