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Furo[3,2-b]pyridine-2-carboxaldehyde (9CI), also known as Furo[3,2-b]pyridine-2-carboxaldehyde, is a chemical compound with the molecular formula C8H5NO. It is a heterocyclic aldehyde featuring a furo[3,2-b]pyridine core structure, which consists of a furan ring fused to a pyridine ring. Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) is recognized for its versatility in organic synthesis and has been extensively studied for its potential biological and pharmacological activities, making it a valuable building block in the development of new molecules with therapeutic and commercial applications.

112372-05-1

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112372-05-1 Usage

Uses

Used in Pharmaceutical Synthesis:
Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic effects. Its unique structure allows for the creation of diverse molecular entities that can target various biological pathways and diseases.
Used in Agrochemical Development:
In the agrochemical industry, Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) is utilized as a starting material for the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used in Organic Synthesis Research:
Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) serves as a versatile building block in organic synthesis, being employed as a reactant in various chemical reactions to form a wide range of organic compounds. Researchers use Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) to explore new synthetic routes and develop innovative methodologies for the preparation of complex molecules with potential applications in materials science, pharmaceuticals, and other fields.
Used in Biological and Pharmacological Studies:
Due to its potential biological and pharmacological activities, Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) is used in research studies to investigate its effects on various biological systems and diseases. Furo[3,2-b]pyridine-2-carboxaldehyde (9CI) holds promise for the discovery of new therapeutic agents, as it may exhibit properties such as anti-inflammatory, antimicrobial, or anticancer activities, among others.

Check Digit Verification of cas no

The CAS Registry Mumber 112372-05-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,3,7 and 2 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 112372-05:
(8*1)+(7*1)+(6*2)+(5*3)+(4*7)+(3*2)+(2*0)+(1*5)=81
81 % 10 = 1
So 112372-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H5NO2/c10-5-6-4-7-8(11-6)2-1-3-9-7/h1-5H

112372-05-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Furo[3,2-b]pyridine-2-carbaldehyde

1.2 Other means of identification

Product number -
Other names 2-formylfuro<3,2-b>pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:112372-05-1 SDS

112372-05-1Relevant articles and documents

COMPOUNS, COMPOSITIONS AND METHODS OF USE

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, (2018/07/29)

Herein, compounds, compositions and methods for modulating inclusion formation and stress granules in cells related to the onset of neurodegenerative diseases, musculoskeletal diseases, cancer, ophthalmological diseases, and viral infections are described.

Selective palladium-catalyzed direct arylation of furo[3,2-b]pyridines

Carrr, Amandine,Florent, Jean-Claude,Bertounesque, Emmanuel,Rousselle, Patricia

, p. 2751 - 2756,6 (2012/12/12)

A method for palladium-catalyzed direct arylation has been developed for the selective functionalization of the C-3 and C-7 positions of 2-substituted furoACHTUNGTRENUNG[3,2-b]pyridines. An unconventional reactivity resulting from the annulation of a pyri

Furo[3,2-b]pyridine: a convenient unit for the synthesis of polyheterocycles

Chartoire, Anthony,Comoy, Corinne,Fort, Yves

, p. 10867 - 10873 (2008/12/23)

An efficient and rapid synthesis of furo[3,2-b]pyridine 1 is described using a one-pot Sonogashira coupling/heteroannulation sequence. Regioselective lithiation of this synthon was performed leading to various 2-substituted furo[3,2-b]pyridines. Some of t

Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction

-

Page/Page column 56, (2008/06/13)

The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B, are as described in the specification.

Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction

-

, (2008/06/13)

The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.

FUSED BICYCLIC AROMATIC COMPOUNDS THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION

-

, (2008/06/13)

The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.

Furopyridines. VII. Preparation and Hydrolysis of 2-Cyano and 3-Cyano Derivatives of Furo-, Furo-, and Furopyridine

Morita, Hiroyuki,Shiotani, Shunsaku

, p. 373 - 376 (2007/10/02)

This paper describes the preparation and hydrolysis of 2-cyano and 3-cyano derivatives of furo-, furo-, and furopyridine.Treatment of furopyridines 1a, 1b and 1c with n-butyllithium in hexane-tetrahydrofuran at -70 deg C and subsequent addition of N,N-dimethylformamide yielded 2-formyl derivatives 2a, 2b and 2c.Dehydration of the oximes 4a, 4b and 4c of 2a, 2b and 2c gave 2-cyano compounds 5a, 5b and 5c, which were hydrolyzed to give 2-carboxylic acids, 6a, 6b and 6c, respectively.Reaction of 3-bromo compounds 7a, 7b and 7c with copper(I) cyanide in N,N-dimethylformamide afforded 3-cyano derivatives 8a, 8b and 8c.Alkaline hydrolysis of 8a, 8b and 8c gave compounds formed by fission of the 1-2 bond of furopyridines 9a, 9b and 9c, while acidic hydrolysis gave the corresponding carboxamides, 10a, 10b and 10c.

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