1130816-79-3

Basic information

• Product Name: (1R,2S)-2-(phenylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-ol
• Synonyms: (1R,2S)-2-(phenylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-ol
• CAS NO: 1130816-79-3
• Molecular Weight: 288.367
• Mol File: 1130816-79-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,2S)-2-(phenylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-2-(phenylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-ol(1130816-79-3)
• EPA Substance Registry System: (1R,2S)-2-(phenylsulfonyl)-1,2,3,4-tetrahydronaphthalen-1-ol(1130816-79-3)

Safety Data

• Hazardous Substances Data: 1130816-79-3(Hazardous Substances Data)

Upstream product

• 51114-72-8 2-(phenylsulfonyl)-3,4-dihydronaphthalen-1(2H)-one 
• 1056246-70-8 2-bromo-1-tetralone 
• 873-55-2 sodium benzenesulfonate 

Relevant articles and documents

A substitution/dynamic kinetic resolution - Asymmetric transfer hydrogenation tandem process for preparation of stereocenters Β-hydroxy sulfones

A noval method for the synthesis of optically active β-hydroxy sulfones was developed. Through a substitution/dynamic kinetic resolution-asymmetric transfer hydrogenation, the presented method was based on one-pot enantioselective organic transformations of α-bromoindenones and sodium arylsulfinate. The protocol employed RuCl2[(S,S)-TsDPEN](mesitylene) as a catalyst, and sodium formate as a hydrogen source, affording various optically pure vicinal stereocenters β-hydroxy sulfones in high yields with excellent enantioselectivities (up to 99%) and diastereomeric ratios (up to 99:1) under mild reaction conditions.