115964-19-7

Basic information

• Product Name: 4,5-DICHLORO-1H-PYRAZOLE-3-CARBOXYLIC ACID
• Synonyms: 4,5-DICHLORO-1H-PYRAZOLE-3-CARBOXYLIC ACID
• CAS NO: 115964-19-7
• Molecular Formula: C4H2Cl2N2O2
• Molecular Weight: 180.97688
• EINECS: -0
• Mol File: 115964-19-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,5-DICHLORO-1H-PYRAZOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DICHLORO-1H-PYRAZOLE-3-CARBOXYLIC ACID(115964-19-7)
• EPA Substance Registry System: 4,5-DICHLORO-1H-PYRAZOLE-3-CARBOXYLIC ACID(115964-19-7)

Safety Data

• Hazardous Substances Data: 115964-19-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4,5-Dichloro-1H-pyrazole-3-carboxylic acid is used as a building block for the synthesis of various drugs and bioactive compounds. Its unique chemical structure allows for the development of new pharmaceuticals with potential therapeutic benefits.
Used in Research and Development:
4,5-DICHLORO-1H-PYRAZOLE-3-CARBOXYLIC ACID is utilized in research and development activities to study the biological activities and properties of pyrazole derivatives. Understanding its interactions with biological systems can lead to the discovery of new applications and improvements in existing pharmaceuticals.
Used in Agrochemicals:
4,5-Dichloro-1H-pyrazole-3-carboxylic acid may have potential uses in agrochemicals, where its chemical properties can be harnessed to develop new products for agricultural applications, such as pesticides or herbicides.
Used in Other Industrial Applications:
Due to its unique chemical structure, 4,5-Dichloro-1H-pyrazole-3-carboxylic acid may also find use in other industrial applications where its properties can be leveraged to create new products or improve existing ones.

Upstream product

• 881668-70-8 5-chloro-1H-pyrazole-3-carboxylic acid 

Relevant articles and documents

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

Investigation of 1N-substituted pyrazole-3-carboxanilides as 15-lipoxygenase-1 (15-LOX-1) inhibitors demonstrated that the 1N-substituent was not essential for activity or selectivity. Additional halogen substituents on the pyrazole ring, however, increased activity. Further development led to triazole-4-carboxanilides and 2-(3-pyrazolyl) benzoxazoles, which are potent and selective 15-LOX-1 inhibitors.

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein R1, R2, A1, A2, A3 and A4 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activit

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.

PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein R1, R2, X1, X2 and n have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15-lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.