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1170-76-9

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1170-76-9 Usage

Chemical Properties

White powder

Uses

Substrate for carboxypeptidase A.

Check Digit Verification of cas no

The CAS Registry Mumber 1170-76-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,7 and 0 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1170-76:
(6*1)+(5*1)+(4*7)+(3*0)+(2*7)+(1*6)=59
59 % 10 = 9
So 1170-76-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H20N2O5/c22-17(12-20-19(25)26-13-15-9-5-2-6-10-15)21-16(18(23)24)11-14-7-3-1-4-8-14/h1-10,16H,11-13H2,(H,20,25)(H,21,22)(H,23,24)/t16-/m0/s1

1170-76-9 Well-known Company Product Price

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  • Aldrich

  • (96260)  Z-Gly-Phe  ≥99.0%

  • 1170-76-9

  • 96260-1G

  • 489.06CNY

  • Detail

1170-76-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-phenyl-2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]propanoic acid

1.2 Other means of identification

Product number -
Other names Benzyloxycarbonylglycyl-L-phenylalanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1170-76-9 SDS

1170-76-9Relevant articles and documents

-

Anderson,Paul

, p. 4423 (1958)

-

A proposal for using mild bases in the preparation of optically pure peptides.

Sakakibara,Ito

, p. 656 - 661 (1967)

-

Direct Hydroxylation of Benzene to Phenol by Cytochrome P450BM3 Triggered by Amino Acid Derivatives

Shoji, Osami,Yanagisawa, Sota,Stanfield, Joshua Kyle,Suzuki, Kazuto,Cong, Zhiqi,Sugimoto, Hiroshi,Shiro, Yoshitsugu,Watanabe, Yoshihito

supporting information, p. 10324 - 10329 (2017/08/22)

The selective hydroxylation of benzene to phenol, without the formation of side products resulting from overoxidation, is catalyzed by cytochrome P450BM3 with the assistance of amino acid derivatives as decoy molecules. The catalytic turnover rate and the total turnover number reached 259 min?1 P450BM3?1 and 40 200 P450BM3?1 when N-heptyl-l-proline modified with l-phenylalanine (C7-l-Pro-l-Phe) was used as the decoy molecule. This work shows that amino acid derivatives with a totally different structure from fatty acids can be used as decoy molecules for aromatic hydroxylation by wild-type P450BM3. This method for non-native substrate hydroxylation by wild-type P450BM3 has the potential to expand the utility of P450BM3 for biotransformations.

Kinetically controlled peptide synthesis mediated by papain using the carbamoylmethyl ester as an acyl donor

Miyazawa, Toshifumi,Horimoto, Takao,Tanaka, Kayoko

, p. 371 - 376 (2014/08/18)

A series of dipeptides were synthesized generally in good yields with carbamoylmethyl (Cam) esters as acyl donors in the presence of a cysteine protease, papain, immobilized on Celite. Several segment condensations were also achieved generally in high yields without danger of racemization and formation of the secondary-hydrolysis product. Moreover, partial sequences of some bioactive peptides were prepared through segment condensations, and aimed-at peptides were obtained generally in high yields without the racemization of C-terminal residues of the carboxyl components. Thus, the superiority of the Cam ester in the kinetically controlled peptide synthesis was once again ascertained in couplings mediated by the cysteine protease as in those catalyzed by the serine proteases reported earlier.

Synthesis and antimalarial bioassay of quinine - peptide conjugates

Panda, Siva S.,Ibrahim, Mohamed A.,Kuecuekbay, Hasan,Meyers, Marvin J.,Sverdrup, Francis M.,El-Feky, Said A.,Katritzky, Alan R.

, p. 361 - 366 (2013/10/08)

Amino acid and peptide conjugates of quinine were synthesized using microwave irradiation in 52-95% yields using benzotriazole methodology. The majority of these conjugates retain in vitro antimalarial activity with IC50 values below 100 nm, similar to quinine.

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