117519-13-8

Basic information

• Product Name: 6-chloro-2-(trifluoromethyl)pyridin-3-amine
• CAS NO: 117519-13-8
• Molecular Weight: 196.559
• Mol File: 117519-13-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-chloro-2-(trifluoromethyl)pyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-(trifluoromethyl)pyridin-3-amine(117519-13-8)
• EPA Substance Registry System: 6-chloro-2-(trifluoromethyl)pyridin-3-amine(117519-13-8)

Safety Data

• Hazardous Substances Data: 117519-13-8(Hazardous Substances Data)

Usage

General Description

6-chloro-2-(trifluoromethyl)pyridin-3-amine is a chemical compound containing a pyridine ring with a chlorine and trifluoromethyl group attached. It is commonly used in the pharmaceutical and agrochemical industries as an intermediate in the synthesis of various biologically active compounds. 6-chloro-2-(trifluoromethyl)pyridin-3-amine has been found to have potential applications in the development of new drugs and agricultural products due to its unique structure and properties. It is also used as a building block in the synthesis of complex organic molecules. Additionally, it may have other industrial applications in fields such as materials science and specialty chemicals.

Upstream product

• 261635-83-0 6-chloro-2-(trifluoromethyl)pyridine-3-carboxylic acid 
• 261635-82-9 ethyl 6-chloro-2-(trifluoromethyl)pyridine-3-carboxylate 
• 208517-35-5 ethyl 2-(trifluoromethyl)pyridine-3-carboxylate 
• 117519-19-4 5-nitro-6-(trifluoromethyl)pyridin-2(1H)-one 
• 117519-12-7 6-chloro-3-nitro-2-(trifluoromethyl)pyridine 
• 887144-97-0 Togni's reagent 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 

Relevant articles and documents

HERBICIDES

The present invention relates to herbicidally active pyridino-/pyrimidino-pyridine derivatives. The invention further provides processes and intermediates used for the preparation of such derivatives. The invention further extends to herbicidal compositions comprising such derivatives, as well as to the use of such compounds and compositions in controlling undesirable plant growth: in particular the use in controlling weeds, in crops of useful plants.

Electrophilic trifluoromethylation of arenes and N-heteroarenes using hypervalent iodine reagents

The reaction of hypervalent iodine trifluoromethylating reagents with a variety of arenes and N-heteroarenes gives access to the corresponding trifluoromethylated compounds. In comparative studies, 1-trifluoromethyl-1,3- dihydro-3,3-dimethyl-1,2-benziodoxole (2) proved to be the superior to 1-trifluoromethyl-1,2-benziodoxol-3-(1H)-one (1) for the direct aromatic trifluoromethylation. Depending on the individual substrates, additives such as zinc bis(trifluoromethylsulfonyl)imide or tris(trimethylsilyl)silyl chloride proved helpful in promoting the reactions. In the case of nitrogen heterocycles a pronounced tendency for the incorporation of the trifluoromethyl group at the position adjacent to nitrogen was observed.