118157-94-1

Basic information

• Product Name: 3,6-DIMETHYL-4-HYDROXYCOUMARIN
• Synonyms: 4-HYDROXY-3,6-DIMETHYL-CHROMEN-2-ONE;3,6-DIMETHYL-4-HYDROXYCOUMARIN;2H-1-Benzopyran-2-one, 4-hydroxy-3,6-diMethyl-
• CAS NO: 118157-94-1
• Molecular Formula: C11H10O3
• Molecular Weight: 190.2
• Mol File: 118157-94-1.mol

Chemical Properties

• Boiling Point: 361.3°C at 760 mmHg
• Flash Point: 161.8°C
• Appearance: /
• Density: 1.299g/cm³
• Vapor Pressure: 7.48E-06mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 3,6-DIMETHYL-4-HYDROXYCOUMARIN(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-DIMETHYL-4-HYDROXYCOUMARIN(118157-94-1)
• EPA Substance Registry System: 3,6-DIMETHYL-4-HYDROXYCOUMARIN(118157-94-1)

Safety Data

• Hazardous Substances Data: 118157-94-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3,6-DIMETHYL-4-HYDROXYCOUMARIN is used as an active pharmaceutical ingredient for its antioxidant and anti-inflammatory properties, contributing to the development of treatments for various diseases, including cancer and inflammation-related disorders.
Used in Fragrance Industry:
3,6-DIMETHYL-4-HYDROXYCOUMARIN is used as a fragrance ingredient due to its unique scent, enhancing the aroma of various perfumes and scented products.
Used in Dye Synthesis:
3,6-DIMETHYL-4-HYDROXYCOUMARIN is used as a key intermediate in the synthesis of dyes, contributing to the coloration of textiles, plastics, and other materials.
Used in Perfume Formulation:
3,6-DIMETHYL-4-HYDROXYCOUMARIN is used as a fixative in perfumes, helping to stabilize and prolong the scent of fragrances.
Used in Flavoring Agent Production:
3,6-DIMETHYL-4-HYDROXYCOUMARIN is used as a flavoring agent in the food and beverage industry, imparting unique taste profiles to various products.
Overall, 3,6-DIMETHYL-4-HYDROXYCOUMARIN's diverse applications across different industries underscore its importance as a versatile chemical compound with significant industrial and medicinal potential.

InChI:InChI=1/C11H10O3/c1-6-3-4-9-8(5-6)10(12)7(2)11(13)14-9/h3-5,12H,1-2H3

Upstream product

• 755009-20-2 6-methyl-2-methylamino-4-oxo-4H-chromene-3-carbaldehyde 
• 755009-17-7 2-ethylamino-6-methyl-4-oxo-4H-chromene-3-carbaldehyde 
• 68301-75-7 2-amino-6-methylchromone-3-carboxaldehyde 
• 22717-57-3 methyl 6-hydroxy-m-toluate 

Relevant articles and documents

Amine-controlled reduction of 2-aminochromone-3-carbaldehyde with Zn and acetic acid

On heating with zinc in acetic acid 2-(N-arylamino)chromone-3-carbaldehydes produce 2-(N-arylamino)-3-methylchromones, whereas 2-(N-alkylamino)chromone-3-carbaldehydes produce 4-hydroxy-3-methylcoumarin in moderate yields. Reduction of an aldehyde functio

Synthesis of coumarins, 4-hydroxycoumarins, and 4-hydroxyquinolinones by tellurium-triggered cyclizations

Coumarins, 4-hydroxycoumarins, and 4-hydroxyquinolin-2(1H)-ones can be conveniently prepared by treatment of α-halocarboxylic acid esters of salicylaldehyde, o-hydroxyacetophenone, methyl salicylate, and methyl N-methyl- or N-phenylanthranilates with sodium or lithium telluride. Phenylketene formation competes with cyclization of the α-chlorophenylacetate ester of methyl salicylate as demonstrated by a trapping experiment with benzylamine. Elemental tellurium may be recovered and reused.