1182367-50-5Relevant articles and documents
Design, synthesis, and preclinical characterization of the selective androgen receptor modulator (SARM) RAD140
Miller, Chris P.,Shomali, Maysoun,Lyttle, C. Richard,O'dea, Louis St. L.,Herendeen, Hillary,Gallacher, Kyla,Paquin, Dottie,Compton, Dennis R.,Sahoo, Bishwabhusan,Kerrigan, Sean A.,Burge, Matthew S.,Nickels, Michael,Green, Jennifer L.,Katzenellenbogen, John A.,Tchesnokov, Alexei,Hattersley, Gary
, p. 124 - 129 (2011/04/15)
This report describes the discovery of RAD140, a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator (SARM). The characterization of RAD140 in several preclinical models of anabolic androgen action is also described.